Neurogenetics
Recent articles
Viral remnant in chimpanzees silences brain gene humans still use
The retroviral insert appears to inadvertently switch off a gene involved in brain development.
Viral remnant in chimpanzees silences brain gene humans still use
The retroviral insert appears to inadvertently switch off a gene involved in brain development.
Long-read sequencing unearths overlooked autism-linked variants
Strips that are thousands of base pairs in length offer better resolution of structural variants and tandem repeats, according to two independent preprints.
Long-read sequencing unearths overlooked autism-linked variants
Strips that are thousands of base pairs in length offer better resolution of structural variants and tandem repeats, according to two independent preprints.
Autism-linked copy number variants always boost autism likelihood
By contrast, varied doses of the same genes decrease or increase the odds of five other conditions, with distinct biological consequences, two new preprints show.
Autism-linked copy number variants always boost autism likelihood
By contrast, varied doses of the same genes decrease or increase the odds of five other conditions, with distinct biological consequences, two new preprints show.
Why hasn’t genetics taught us more about schizophrenia?
Large-scale genomics studies have failed to identify specific pathways that go awry in schizophrenia. Alternative approaches focusing on cellular, molecular and systems-level changes may be needed.
Why hasn’t genetics taught us more about schizophrenia?
Large-scale genomics studies have failed to identify specific pathways that go awry in schizophrenia. Alternative approaches focusing on cellular, molecular and systems-level changes may be needed.
On the hunt for cerebral palsy’s genetic origins
Two recent papers suggest genes can play a significant role, findings that could change diagnosis and treatment of the condition.
On the hunt for cerebral palsy’s genetic origins
Two recent papers suggest genes can play a significant role, findings that could change diagnosis and treatment of the condition.
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Frameshift: Raphe Bernier followed his heart out of academia, then made his way back again
After a clinical research career, an interlude at Apple and four months in early retirement, Raphe Bernier found joy in teaching.
Frameshift: Raphe Bernier followed his heart out of academia, then made his way back again
After a clinical research career, an interlude at Apple and four months in early retirement, Raphe Bernier found joy in teaching.
Organoid study reveals shared brain pathways across autism-linked variants
The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.
Organoid study reveals shared brain pathways across autism-linked variants
The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.
Single gene sways caregiving circuits, behavior in male mice
Brain levels of the agouti gene determine whether African striped mice are doting fathers—or infanticidal ones.
Single gene sways caregiving circuits, behavior in male mice
Brain levels of the agouti gene determine whether African striped mice are doting fathers—or infanticidal ones.