Organoids
Recent articles
Novel assembloid illuminates serotonin changes linked to 22q11.2 deletion
The combination of a serotonin-producing organoid with an organoid based on the developing cerebral cortex offers a new way to investigate neuromodulation.
Novel assembloid illuminates serotonin changes linked to 22q11.2 deletion
The combination of a serotonin-producing organoid with an organoid based on the developing cerebral cortex offers a new way to investigate neuromodulation.
Organoid study reveals shared brain pathways across autism-linked variants
The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.
Organoid study reveals shared brain pathways across autism-linked variants
The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.
Viral remnant in chimpanzees silences brain gene humans still use
The retroviral insert appears to inadvertently switch off a gene involved in brain development.
Viral remnant in chimpanzees silences brain gene humans still use
The retroviral insert appears to inadvertently switch off a gene involved in brain development.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
New organoid atlas unveils four neurodevelopmental signatures
The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.
New organoid atlas unveils four neurodevelopmental signatures
The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.
What is the future of organoid and assembloid regulation?
Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.
What is the future of organoid and assembloid regulation?
Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.
What are the most transformative neuroscience tools and technologies developed in the past five years?
Artificial intelligence and deep-learning methods featured prominently in the survey responses, followed by genetic tools to control circuits, advanced neuroimaging, transcriptomics and various approaches to record brain activity and behavior.
What are the most transformative neuroscience tools and technologies developed in the past five years?
Artificial intelligence and deep-learning methods featured prominently in the survey responses, followed by genetic tools to control circuits, advanced neuroimaging, transcriptomics and various approaches to record brain activity and behavior.
‘Neuroethics: The Implications of Mapping and Changing the Brain,’ an excerpt
In his new book, published today, philosopher Walter Glannon examines the ethics of six areas of neuroscience. In Chapter 4, a portion of which appears below, he tackles the ethical considerations of using brain organoids in research.
‘Neuroethics: The Implications of Mapping and Changing the Brain,’ an excerpt
In his new book, published today, philosopher Walter Glannon examines the ethics of six areas of neuroscience. In Chapter 4, a portion of which appears below, he tackles the ethical considerations of using brain organoids in research.
Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”
Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”
NIH proposal sows concerns over future of animal research, unnecessary costs
The new NIH policy calls for greater incorporation of new approach methodologies in all future Notices of Funding Opportunities related to animal model systems.
NIH proposal sows concerns over future of animal research, unnecessary costs
The new NIH policy calls for greater incorporation of new approach methodologies in all future Notices of Funding Opportunities related to animal model systems.
Explore more from The Transmitter
European Research Council backtracks on stricter grant resubmission rules
The swift reversal came after more than 1,000 scientists signed an open letter protesting the rules last week.
European Research Council backtracks on stricter grant resubmission rules
The swift reversal came after more than 1,000 scientists signed an open letter protesting the rules last week.
What leeches reveal about movement
After encountering setbacks in her study of the neuromuscular system in vertebrates, Lidia Szczupak turned to leeches to explore how the nervous system coordinates movement.
What leeches reveal about movement
After encountering setbacks in her study of the neuromuscular system in vertebrates, Lidia Szczupak turned to leeches to explore how the nervous system coordinates movement.
Reporter’s notebook: Highlights from INSAR 2026
At the 25th annual meeting of the International Society for Autism Research, scientists, clinicians and self-advocates gathered to discuss topics such as autism genetics and the gap between clinical trials and real-world benefits.
Reporter’s notebook: Highlights from INSAR 2026
At the 25th annual meeting of the International Society for Autism Research, scientists, clinicians and self-advocates gathered to discuss topics such as autism genetics and the gap between clinical trials and real-world benefits.