Psychiatric disorders
Recent articles
Chris Rozell explains how brain stimulation and AI are helping to treat mental disorders
Rozell and his colleagues, using deep brain stimulation and explainable artificial intelligence, have developed tools to help people with treatment-resistant depression.
Chris Rozell explains how brain stimulation and AI are helping to treat mental disorders
Rozell and his colleagues, using deep brain stimulation and explainable artificial intelligence, have developed tools to help people with treatment-resistant depression.
Nicole Rust on her new book, ‘Elusive Cures’
Rust discusses how understanding the brain as a complex dynamical system will help us accelerate treatments for brain disorders.
Nicole Rust on her new book, ‘Elusive Cures’
Rust discusses how understanding the brain as a complex dynamical system will help us accelerate treatments for brain disorders.
‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt
In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community’s “Grand Plan.”

‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt
In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community’s “Grand Plan.”
Sharing Africa’s brain data: Q&A with Amadi Ihunwo
These data are “virtually mandatory” to advance neuroscience, says Ihunwo, a co-investigator of the Brain Research International Data Governance & Exchange (BRIDGE) initiative, which seeks to develop a global framework for sharing, using and protecting neuroscience data.

Sharing Africa’s brain data: Q&A with Amadi Ihunwo
These data are “virtually mandatory” to advance neuroscience, says Ihunwo, a co-investigator of the Brain Research International Data Governance & Exchange (BRIDGE) initiative, which seeks to develop a global framework for sharing, using and protecting neuroscience data.
The brain’s quiet conductor: How hidden cells fine-tune arousal
New research published today suggests that the pericoeruleus acts as a kind of micromanager of arousal, selectively inhibiting different subgroups of locus coeruleus neurons depending on the behavioral context.
The brain’s quiet conductor: How hidden cells fine-tune arousal
New research published today suggests that the pericoeruleus acts as a kind of micromanager of arousal, selectively inhibiting different subgroups of locus coeruleus neurons depending on the behavioral context.
Lions and tigers and bears: Long-lived zoo animals offer a promising venue to study mental health and neurodegenerative disorders
These animals’ lifestyles often mirror those of people, making them a more relevant milieu than lab mice for determining how environmental factors influence mental health and cognitive decline. Studying them could improve animal welfare in the process.

Lions and tigers and bears: Long-lived zoo animals offer a promising venue to study mental health and neurodegenerative disorders
These animals’ lifestyles often mirror those of people, making them a more relevant milieu than lab mice for determining how environmental factors influence mental health and cognitive decline. Studying them could improve animal welfare in the process.
Why hasn’t genetics taught us more about schizophrenia?
Large-scale genomics studies have failed to identify specific pathways that go awry in schizophrenia. Alternative approaches focusing on cellular, molecular and systems-level changes may be needed.

Why hasn’t genetics taught us more about schizophrenia?
Large-scale genomics studies have failed to identify specific pathways that go awry in schizophrenia. Alternative approaches focusing on cellular, molecular and systems-level changes may be needed.
Rethinking mental health: The body’s impact on the brain
Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.

Rethinking mental health: The body’s impact on the brain
Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.
What, if anything, makes mood fundamentally different from memory?
To better understand mood disorders—and to develop more effective treatments—should we target the brain, the mind, the environment or all three?

What, if anything, makes mood fundamentally different from memory?
To better understand mood disorders—and to develop more effective treatments—should we target the brain, the mind, the environment or all three?
Physicians who oversaw diagnostic manual’s revision had pharma funding
Of the 92 U.S.-based physicians who worked on the latest edition of the Diagnostic and Statistical Manual of Mental Disorders, 55 of them have collectively received millions of dollars from drug and device companies, new research shows.

Physicians who oversaw diagnostic manual’s revision had pharma funding
Of the 92 U.S.-based physicians who worked on the latest edition of the Diagnostic and Statistical Manual of Mental Disorders, 55 of them have collectively received millions of dollars from drug and device companies, new research shows.
Explore more from The Transmitter
Emotion research has a communication conundrum
In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.

Emotion research has a communication conundrum
In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.
Autism-linked copy number variants always boost autism likelihood
By contrast, varied doses of the same genes decrease or increase the odds of five other conditions, with distinct biological consequences, two new preprints show.

Autism-linked copy number variants always boost autism likelihood
By contrast, varied doses of the same genes decrease or increase the odds of five other conditions, with distinct biological consequences, two new preprints show.
Everything everywhere all at once: Decision-making signals engage entire brain
The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.

Everything everywhere all at once: Decision-making signals engage entire brain
The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.