- A gene therapy administered after birth reverses disruptions in brain development observed in mice missing the FOXG1 gene. Spectrum previously reported on researchers whose work focuses on their own children’s conditions, as Soo-Kyung Lee has done with FOXG1 syndrome. The Scientist
- “Our findings highlight that patterns of age-related changes in the brain may be influenced by demographic and phenotypic characteristics, and thus future studies should consider these when examining or controlling for age effects in analyses.” Human Brain Mapping
- Zebrafish with autism-linked genetic variants show both altered auditory responses—hypersensitivity and delayed habituation—and brain-wide neuronal activity changes, according to a preprint. bioRxiv
FOXG1 gene therapy; oligodendrocytes; stereotyped movements
Here is a roundup of autism-related news and research spotted around the web for the week of 23 September.
By
Jill Adams
24 September 2024 | 2 min read

Slow learning: Zebrafish missing the autism-linked gene CNTNAP2A (right panel) display lower (light green) functional connectivity in several forebrain areas during an acoustic habituation task than do controls (left panel).
- Mice missing the autism-linked gene SCN2A in their oligodendrocytes show altered myelination and, in turn, changes in neuronal excitability and synaptic plasticity, according to a preprint. Spectrum has reported on the role of oligodendrocytes in autism. Research Square
- Infants with two or more of a suite of behavioral differences are more likely to have autism or other developmental conditions at age 3 than are those without these differences. Autism
- A machine-learning algorithm trained on videos of autistic children’s stereotyped movements can objectively recognize the presence and degree of such motor behaviors. JAMA Network Open
tags:
Recommended reading

Altered translation in SYNGAP1-deficient mice; and more
By
Jill Adams
6 May 2025 | 2 min read

CDC autism prevalence numbers warrant attention—but not in the way RFK Jr. proposes
By
Lynn Waterhouse
1 May 2025 | 6 min read

‘These plans are simply not acceptable’: Q&A with Helen Tager-Flusberg
By
Sydney Wyatt
1 May 2025 | 5 min read
Explore more from The Transmitter

Sleep doesn’t just consolidate memories; it actively shapes them
By
Giorgia Guglielmi
6 May 2025 | 5 min read

Thinking about thinking: AI offers theoretical insights into human memory
By
Terrence Sejnowski
5 May 2025 | 7 min read
Cite this article: