Probing the link between preterm birth and autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 28 July.

Factorial scrutiny: Children who were born preterm have an elevated likelihood of being diagnosed with autism, and yet no genetic or environmental factors clearly account for that relationship, according to a new study. An analysis of 19 population studies found one significant predictive factor for autism in preterm-born children: male sex. Still, the threefold increase in odds linked to sex in babies born before 37 weeks of gestation is similar to that in full-term births. Other variables, such as maternal factors, birth complications and fetal conditions, which past studies had implicated, did not yield significant associations when combined across studies. The study’s authors call for more research. Biological Psychiatry Global Open Science

More autism research we spotted:

  • “CHD8 adulthood microglial knockdown in C57BL6 mice induces behavioral, morphological, and transcriptional changes in a sex-dependent manner” Translational Psychiatry
Research image of dendrites in mice.
Limited reach: Knockdown of the autism-linked gene CHD8 in the microglia of adult mice results in dendrite shortening in males (center) but not females (right) compared with control mice (left).

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