News / Spectrum

Emotional dysregulation; NMDA receptor variation; frank autism

Here is a roundup of autism-related news and research spotted around the web for the week of 25 November.

By Jill Adams

26 November 2024 | 1 min read

Two studies from Carla Mazefsky’s lab describe the prevalence and severity of emotional dysregulation and aggression, respectively, in autistic preschoolers. Autism Research, JAACAP Open
General anxiety disorder does not predict social communication difficulties in school-age autistic children and adolescents. Journal of the Canadian Academy of Child and Adolescent Psychiatry
A clinical trial participant has died after receiving a dose of Neurogene’s Rett syndrome therapy, NGN-401. Endpoints News

Molecular analysis of genetic variants in subunits of the NMDA receptor, some of which contribute to autism and other neurodevelopmental conditions, reveals a relationship between pathogenicity and protein structure. Human Molecular Genetics
Initial impressions of autism traits in adolescents and young adults, used to identify frank autism, generally correlate with formal diagnosis, according to a new study, but nearly a third of autistic people in the work were misidentified as non-autistic. One of the investigators previously authored a Spectrum commentary on the concept of frank, or prototypical, autism. Molecular Autism