Organoids
Recent articles
NIH proposal sows concerns over future of animal research, unnecessary costs
The new NIH policy calls for greater incorporation of new approach methodologies in all future Notices of Funding Opportunities related to animal model systems.

NIH proposal sows concerns over future of animal research, unnecessary costs
The new NIH policy calls for greater incorporation of new approach methodologies in all future Notices of Funding Opportunities related to animal model systems.
Why the 21st-century neuroscientist needs to be neuroethically engaged
Technological advances in decoding brain activity and in growing human brain cells raise new ethical issues. Here is a framework to help researchers navigate them.

Why the 21st-century neuroscientist needs to be neuroethically engaged
Technological advances in decoding brain activity and in growing human brain cells raise new ethical issues. Here is a framework to help researchers navigate them.
In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain
Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.

In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain
Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.
Organoids and assembloids offer a new window into human brain
These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.

Organoids and assembloids offer a new window into human brain
These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.
Thanks to new technologies, neuroscientists have more direct access to the human brain than ever before
Model systems continue to offer us tremendous insight, but it’s time for basic researchers to train their sights on the human brain. If I were starting my career today, I would focus on human neurobiology.

Thanks to new technologies, neuroscientists have more direct access to the human brain than ever before
Model systems continue to offer us tremendous insight, but it’s time for basic researchers to train their sights on the human brain. If I were starting my career today, I would focus on human neurobiology.
Future watch: What should neuroscience prioritize during the next 10 to 20 years?
For The Transmitter’s first annual book, five contributing editors reflect on what subfields demand greater focus in the near future—from dynamical systems and computation to technologies for studying the human brain.

Future watch: What should neuroscience prioritize during the next 10 to 20 years?
For The Transmitter’s first annual book, five contributing editors reflect on what subfields demand greater focus in the near future—from dynamical systems and computation to technologies for studying the human brain.
Assembloids illuminate circuit-level changes linked to autism, neurodevelopment
These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.
Assembloids illuminate circuit-level changes linked to autism, neurodevelopment
These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.
Parasite-based tool delivers MECP2 and other proteins to neurons
A method that uses a common brain parasite could help replenish the proteins deficient in Rett syndrome and other conditions.

Parasite-based tool delivers MECP2 and other proteins to neurons
A method that uses a common brain parasite could help replenish the proteins deficient in Rett syndrome and other conditions.
Is it time to worry about brain chimeras?
Brains made of neurons from two species raise new concerns.

Is it time to worry about brain chimeras?
Brains made of neurons from two species raise new concerns.
Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.

Brain patterning in utero may be implicated in autism, other conditions
Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.
Explore more from The Transmitter
This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations
By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.

This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations
By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.
Prosocial effects of oxytocin are state dependent; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 11 August.

Prosocial effects of oxytocin are state dependent; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 11 August.
The challenge of defining a neural population
Our current approach is largely arbitrary. We need new methods for grouping cells, ideally by their dynamics.

The challenge of defining a neural population
Our current approach is largely arbitrary. We need new methods for grouping cells, ideally by their dynamics.