Statistics

Recent articles

Research images shows areas of cortex that differed across scans of variable quality.

Poor image quality introduces systematic bias into large neuroimaging datasets

Analyses that include low-quality MRI data underestimate cortical thickness and overestimate cortical surface area, according to new findings from the Adolescent Brain Cognitive Development (ABCD) Study.

By Natalia Mesa
31 July 2025 | 7 min listen
Overlapping speech bubbles.

Memory study sparks debate over statistical methods

Critics of a 2024 Nature paper suggest the authors failed to address the risk of false-positive findings. The authors argue more rigorous methods can result in missed leads.

By Katie Moisse
2 July 2025 | 5 min read
An opaque cube is repeated multiple times to create the appearance of overlapping cubes.

Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind

Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.

By Lauren Schenkman
12 June 2025 | 6 min read
A curly line connects two pencils that are hovering over overlapping speech bubbles.

Say what? The Transmitter’s top quotes of 2024

“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.

By The Transmitter
23 December 2024 | 2 min read
Illustration of a single digitally rendered figure wandering a fragmented and distorted virtual environment.

Nonsense correlations and how to avoid them

This statistical error is common in systems neuroscience. Fortunately, straightforward methods can help you prevent it.

By Kenneth Harris
12 August 2024 | 6 min listen

Explore more from The Transmitter

Remembering GABA pioneer Edward Kravitz

The biochemist, who died last month at age 92, was part of the first neurobiology department in the world and showed that gamma-aminobutyric acid is inhibitory.

By Claudia López Lloreda
24 October 2025 | 9 min listen

Protein tug-of-war controls pace of synaptic development, sets human brains apart

Human-specific duplicates of SRGAP2 prolong cortical development by manipulating SYNGAP, an autism-linked protein that slows synaptic growth.

By Holly Barker
23 October 2025 | 9 min listen
Mouse sensory neurons express the ion channel TPRV1 .

Neurons tune electron transport chain to survive onslaught of noxious stimuli

Nociceptors tamp down the production of reactive oxygen species in response to heat, chemical irritants or toxins.

By Viviane Callier
22 October 2025 | 5 min listen

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