Systems neuroscience

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Escaping groupthink: What animals’ behavioral quirks reveal about the brain

Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.

By Angie Voyles Askham
23 May 2025 | 10 min listen
Research image showing resting-state functional connectivity in the human red nucleus.

‘Ancient’ brainstem structure evolved beyond basic motor control

The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.

By Sydney Wyatt
16 May 2025 | 5 min read
Conceptual illustration of four heads studying representations of neural mechanisms.

This paper changed my life: Marino Pagan recalls a decision-making study from four titans in the field

Valerio Mante and David Sussillo, along with their mentors Krishna Shenoy and Bill Newsome, revealed the complexity of neural population dynamics and the power of recurrent neural networks.

By Marino Pagan
13 May 2025 | 7 min listen
Illustration of a treeline in front of a human brain.

‘Natural Neuroscience: Toward a Systems Neuroscience of Natural Behaviors,’ an excerpt

In his new book, published today, Nachum Ulanovsky calls on the field to embrace naturalistic conditions and move away from overcontrolled experiments.

By Nachum Ulanovsky
15 April 2025 | 9 min read
Research image of a fiber optic implant in a mouse brain.

Bespoke photometry system captures variety of dopamine signals in mice

The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.

By Sydney Wyatt
21 March 2025 | 5 min read

Explore more from The Transmitter

Photograph of a chickadee.

Gazing at a location from afar activates place cells in chickadees

The results help explain how the hippocampus can recall information about a place without an animal physically revisiting it.

By Marta Hill
13 June 2025 | 6 min read
An opaque cube is repeated multiple times to create the appearance of overlapping cubes.

Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind

Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.

By Lauren Schenkman
12 June 2025 | 6 min read
Crumpled pieces of paper form an X.

Psychedelics meta-analysis retracted after authors request ‘significant changes’

While working on a similar analysis last year, an independent researcher spotted inconsistencies in the now-retracted paper.

By Marta Hill
11 June 2025 | 2 min read