Amyloid beta
Recent articles
Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease
To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.
Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease
To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.
Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.
Skeptics challenge claims of Alzheimer’s disease transmission via growth hormone
Some people who received cadaver-derived human growth hormone may not have Alzheimer’s as previously suggested, according to a new Perspective article.
Skeptics challenge claims of Alzheimer’s disease transmission via growth hormone
Some people who received cadaver-derived human growth hormone may not have Alzheimer’s as previously suggested, according to a new Perspective article.
Putting a bright idea to the test
A surprising wave of findings in mice suggests that light and sound flickering at 40 hertz clears the brain of Alzheimer’s-disease-linked plaques. Several companies are hoping to prove it works in people.
Putting a bright idea to the test
A surprising wave of findings in mice suggests that light and sound flickering at 40 hertz clears the brain of Alzheimer’s-disease-linked plaques. Several companies are hoping to prove it works in people.
Reviving ‘inside-out’ hypothesis of amyloid beta to explain Alzheimer’s mysteries
New research is resurfacing old ideas about where the protein forms the disease’s hallmark plaques.
Reviving ‘inside-out’ hypothesis of amyloid beta to explain Alzheimer’s mysteries
New research is resurfacing old ideas about where the protein forms the disease’s hallmark plaques.
How inbreeding almost tanked an up-and-coming model of Alzheimer’s disease
But new genetic analyses and behavioral assays have made the Chilean degu a viable model again, researchers say.
How inbreeding almost tanked an up-and-coming model of Alzheimer’s disease
But new genetic analyses and behavioral assays have made the Chilean degu a viable model again, researchers say.
Carol Jennings, whose family’s genetics informed amyloid cascade hypothesis, dies at 70
Her advocacy work aided the discovery of a rare inherited form of early-onset Alzheimer’s disease and helped connect affected people with researchers.
Carol Jennings, whose family’s genetics informed amyloid cascade hypothesis, dies at 70
Her advocacy work aided the discovery of a rare inherited form of early-onset Alzheimer’s disease and helped connect affected people with researchers.
Explore more from The Transmitter
Newly identified barrier cells seal off choroid plexus from CSF, rest of brain
A long-overlooked layer of fibroblasts exists inside the choroid plexus of mice and humans, adding complexity to the area’s compartmentalization.
Newly identified barrier cells seal off choroid plexus from CSF, rest of brain
A long-overlooked layer of fibroblasts exists inside the choroid plexus of mice and humans, adding complexity to the area’s compartmentalization.
‘Digital sphinx’ raises questions about connectome models
The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
‘Digital sphinx’ raises questions about connectome models
The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
Taking a closer look at astrocytes and autism
These glial cells are increasingly linked to neurodevelopmental conditions and the regulation of social behaviors and anxiety.
Taking a closer look at astrocytes and autism
These glial cells are increasingly linked to neurodevelopmental conditions and the regulation of social behaviors and anxiety.