Blood-brain barrier

Recent articles

DNA helix.

Advances in genetic medicine took center stage at INSAR

The president of the Autism Science Foundation and parent of a child with profound autism reflects on how advances in the treatment of rare gene variants bring hope to many families.

By Alison Singer
5 May 2026 | 4 min read
Research image of fibroblasts creating a seal that separates the blood vessels in the choroid plexus from the rest of the brain.

Newly identified barrier cells seal off choroid plexus from CSF, rest of brain

A long-overlooked layer of fibroblasts exists inside the choroid plexus of mice and humans, adding complexity to the area’s compartmentalization.

By Claudia López Lloreda
3 April 2026 | 4 min read
Research image of a mouse brain with the same spot shown three times in different colors to show different neurochemical concentrations.

New dopamine sensor powers three-color imaging in live animals

The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.

By Diana Kwon
25 July 2025 | 4 min read
Astrocytes in a mouse brain.

Unexpected astrocyte gene flips image of brain’s ‘stalwart sentinels’

The genetic marker upends the accepted orientation of non-star-like astrocytes in the glia limitans superficialis.

By Lauren Schenkman
28 March 2025 | 5 min read
Illustration of a lab with a smoking crater in the middle of the floor.

The Transmitter’s favorite features of 2024

Our chosen stories include tales about research misconduct in the lab, a neuroscientist working at the end of the world, and the passing of neuroanatomy’s “great-grandfather,” Harvey Karten.

By The Transmitter
23 December 2024 | 2 min read
Research image of mouse cells.

Immune cell interlopers breach—and repair—brain barrier in mice

The choroid plexus, the protective network of blood vessels and epithelial cells that line the brain’s ventricles, recruits neutrophils and macrophages during inflammation, a new study shows.

By Claudia López Lloreda
20 November 2024 | 6 min read
Maiken Nedergaard, Britta Engelhardt and Christer Betsholtz on a floating rock island with university facilities and abstract shapes.

Maiken Nedergaard’s power of disruption

The award-winning researcher’s discoveries have changed the way we think about the brain; that’s exactly what her critics dislike.

By Emily Sohn
26 February 2024 | 24 min read

Explore more from The Transmitter

Alison Barth discovers how different neuron types contribute to cortical function

Barth uses learning tasks in mice as a tool to drive synaptic plasticity in the sensory cortex, hoping to unlock more general principles of how the cortex works.

By Paul Middlebrooks
5 August 2026 | 1 min read
Mouse muscle cells.

Virus-like particles deliver gene-editing tools into Duchenne mouse model

The approach uses a protein found in fruit flies to ferry the gene editor Cas9 into muscle cells.

By Brianna Abbott
5 August 2026 | 5 min read

Textbook model of hippocampus’s role in memory may need updating

The CA3 region, long thought to have just one circuit, has two, sporting different wiring and functions, a new preprint suggests.

By Alissa de Chassey
4 August 2026 | 5 min read