Common variants
Recent articles
Genetic profiles separate early, late autism diagnoses
Age at diagnosis reflects underlying differences in common genetic variants and developmental trajectories among people with autism.
Genetic profiles separate early, late autism diagnoses
Age at diagnosis reflects underlying differences in common genetic variants and developmental trajectories among people with autism.
Sequencing study spotlights tight web of genes tied to autism
The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.
Sequencing study spotlights tight web of genes tied to autism
The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
Giant analysis reveals how autism-linked genes affect brain cell types
Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.
Giant analysis reveals how autism-linked genes affect brain cell types
Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.
Common genetic variants shape the structure of the cortex
A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.
Common genetic variants shape the structure of the cortex
A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.
Head size parts autism into two major subtypes
An imbalance in the number of excitatory neurons in early brain development may account for the difference.
Head size parts autism into two major subtypes
An imbalance in the number of excitatory neurons in early brain development may account for the difference.
Some who lack autism diagnosis carry variants tied to the condition
The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.
Some who lack autism diagnosis carry variants tied to the condition
The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.
Genetic background sways effects of autism-linked mutation
Experiments offer clues to why certain mutations are associated with autism in some people and not others.
Genetic background sways effects of autism-linked mutation
Experiments offer clues to why certain mutations are associated with autism in some people and not others.
Common and rare autism-linked variants share functional effects
Within the 16p region of the genome, the two types of variants similarly decrease neuronal gene expression — an effect that may reflect their spatial relationship.
Common and rare autism-linked variants share functional effects
Within the 16p region of the genome, the two types of variants similarly decrease neuronal gene expression — an effect that may reflect their spatial relationship.
A mix of common and rare variants shapes autism inheritance patterns
The study also reveals a link between language development and common variants.
A mix of common and rare variants shapes autism inheritance patterns
The study also reveals a link between language development and common variants.
Explore more from The Transmitter
To persist, memories surf molecular waves from thalamus to cortex
During the later stages of learning, the mouse brain progressively activates transcriptional regulators that drive memory consolidation.
To persist, memories surf molecular waves from thalamus to cortex
During the later stages of learning, the mouse brain progressively activates transcriptional regulators that drive memory consolidation.
Sex hormone boosts female rats’ sensitivity to unexpected rewards
During the high-estradiol stages of their estrus cycle, female rats learn faster than they do during other stages—and than male rats overall—thanks to a boost in their dopaminergic response to reward, a new study suggests.
Sex hormone boosts female rats’ sensitivity to unexpected rewards
During the high-estradiol stages of their estrus cycle, female rats learn faster than they do during other stages—and than male rats overall—thanks to a boost in their dopaminergic response to reward, a new study suggests.
SHANK3 deficiency and behavior in mice; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 24 November.
SHANK3 deficiency and behavior in mice; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 24 November.