Brian O’Roak uses genomic approaches to unlock the genetic basis of neurodevelopmental disorders such as autism and intellectual disability.
Brian O’Roak
Associate professor of molecular and medical genetics
Oregon Health and Science University
From this contributor
How I learned to stop worrying and love preprints
Preprints are gaining traction in biology, but some researchers have lingering concerns. Should they?
Burning debate: What’s the best way to nab real autism genes?
How to best use a large volume of data to discover new genetic risk factors for autism is a matter of intense debate, particularly in light of historical challenges.

Burning debate: What’s the best way to nab real autism genes?
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New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.

New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
How to build a truly global computational neuroscience community
Computational sciences offer an opportunity to increase global access to, and participation in, neuroscience. Neuromatch’s inclusive, scalable model for community building shows how to realize this promise.

How to build a truly global computational neuroscience community
Computational sciences offer an opportunity to increase global access to, and participation in, neuroscience. Neuromatch’s inclusive, scalable model for community building shows how to realize this promise.