Brian O’Roak

Associate professor of molecular and medical genetics
Oregon Health and Science University

Brian O’Roak uses genomic approaches to unlock the genetic basis of neurodevelopmental disorders such as autism and intellectual disability.

From this contributor

Figures along the top of a cliff, reaching for the papers falling from the sky and circulating in the air currents.
Spectrum

How I learned to stop worrying and love preprints

By Brian O’Roak
22 May 2018 | 7 min read
Spectrum Microphone

Burning debate: What’s the best way to nab real autism genes?

By Brian O’Roak
27 June 2017 | 9 min read

Explore more from The Transmitter

Spectrum

Among brain changes studied in autism, spotlight shifts to subcortex

The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.

By Holly Barker
11 December 2025 | 5 min read
Brain organoid.
Organoids Microphone

What is the future of organoid and assembloid regulation?

Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.

By Claudia López Lloreda
10 December 2025 | 7 min read
Research image of variants of the ATPase subunit PSMC5/RPT6.
Spectrum

Insights on suicidality and autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 8 December.

By Jill Adams
9 December 2025 | 2 min read

privacy consent banner

Privacy Preference

We use cookies to provide you with the best online experience. By clicking “Accept All,” you help us understand how our site is used and enhance its performance. You can change your choice at any time. To learn more, please visit our Privacy Policy.