Brian O’Roak uses genomic approaches to unlock the genetic basis of neurodevelopmental disorders such as autism and intellectual disability.
Brian O’Roak
Associate professor of molecular and medical genetics
Oregon Health and Science University
From this contributor
How I learned to stop worrying and love preprints
Preprints are gaining traction in biology, but some researchers have lingering concerns. Should they?
Burning debate: What’s the best way to nab real autism genes?
How to best use a large volume of data to discover new genetic risk factors for autism is a matter of intense debate, particularly in light of historical challenges.
Burning debate: What’s the best way to nab real autism genes?
By
Brian O’Roak
27 June 2017 | 9 min read
Explore more from The Transmitter
The illusion of AI consciousness: Lessons from human unconscious processing
Complex, goal-directed and even emotionally responsive behavior can unfold without awareness, providing a useful lens for interpreting artificial systems.
The illusion of AI consciousness: Lessons from human unconscious processing
Complex, goal-directed and even emotionally responsive behavior can unfold without awareness, providing a useful lens for interpreting artificial systems.
By
Vanessa Hadid, Karim Jerbi, John W. Krakauer
8 June 2026 | 0 min watch
‘Push-pull’ recipe for neural wiring used in multiple brain regions
A versatile pair of proteins steers neurons toward their targets and helps establish the brain’s sensory maps, new studies suggest.
‘Push-pull’ recipe for neural wiring used in multiple brain regions
A versatile pair of proteins steers neurons toward their targets and helps establish the brain’s sensory maps, new studies suggest.
By
Holly Barker
5 June 2026 | 5 min read
Reward-learning algorithm hardwired into dopamine circuit
The finding bolsters the canonical model of reward prediction error, which has come under scrutiny in recent years.
Reward-learning algorithm hardwired into dopamine circuit
The finding bolsters the canonical model of reward prediction error, which has come under scrutiny in recent years.
By
Natalia Mesa
5 June 2026 | 5 min read