Brian O’Roak uses genomic approaches to unlock the genetic basis of neurodevelopmental disorders such as autism and intellectual disability.
Brian O’Roak
Associate professor of molecular and medical genetics
Oregon Health and Science University
From this contributor
How I learned to stop worrying and love preprints
Preprints are gaining traction in biology, but some researchers have lingering concerns. Should they?
Burning debate: What’s the best way to nab real autism genes?
How to best use a large volume of data to discover new genetic risk factors for autism is a matter of intense debate, particularly in light of historical challenges.
Burning debate: What’s the best way to nab real autism genes?
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The relationship between structure and function in cortical networks
Michael Reimann explains how the shape of neurons puts strong constraints on how they are wired in a network, and how this affects their structure-function relationships.
The relationship between structure and function in cortical networks
Michael Reimann explains how the shape of neurons puts strong constraints on how they are wired in a network, and how this affects their structure-function relationships.
How brains prevent ‘catastrophic forgetting’
Dendrite-specific inhibition lets overlapping neuronal assemblies form across brain areas without erasing existing memories, a new modeling study suggests.
How brains prevent ‘catastrophic forgetting’
Dendrite-specific inhibition lets overlapping neuronal assemblies form across brain areas without erasing existing memories, a new modeling study suggests.
Lipids enter brain mapping limelight
Two new studies, including the first whole-brain lipid atlas in mice, uncover unforeseen complexity and influence during pregnancy and aging.
Lipids enter brain mapping limelight
Two new studies, including the first whole-brain lipid atlas in mice, uncover unforeseen complexity and influence during pregnancy and aging.