Holly Barker is a freelance writer specializing in biology, medicine and psychology. She has a Ph.D. in clinical neuroscience from King’s College London in the United Kingdom and a B.Sc. degree in biochemistry from the University of Manchester. She has previously written for Discover and BioNews. She is based in London.

Holly Barker
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Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.

Worms help untangle brain structure/function mystery
Oxytocin prompts prairie voles to oust outsiders, fortifying their friendships
The “love hormone” drives the neurobiology behind platonic bonds in animals usually studied for their romantic attachments.

Oxytocin prompts prairie voles to oust outsiders, fortifying their friendships
Genetic background steers PTEN syndrome traits
People with the syndrome, caused by variants in the gene PTEN, often have autism or cancer, or both, but it depends on the genetic diversity encoded in the components of distinct cell signaling pathways, according to a new study.
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

Some dopamine neurons signal default behaviors to reinforce habits
Split gene therapy delivers promise in mice modeling Dravet syndrome
The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.

Split gene therapy delivers promise in mice modeling Dravet syndrome
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Diving in with Nachum Ulanovsky
With an eye toward realism, the neuroscientist, who has a new study about bats out today, creates microcosms of the natural world to understand animal behavior.

Diving in with Nachum Ulanovsky
With an eye toward realism, the neuroscientist, who has a new study about bats out today, creates microcosms of the natural world to understand animal behavior.
Gene-activity map of developing brain reveals new clues about autism’s sex bias
Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked variants appearing more often in girls.

Gene-activity map of developing brain reveals new clues about autism’s sex bias
Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked variants appearing more often in girls.
Engrams in amygdala lean on astrocytes to solidify memories
Disrupting the astrocyte-neuronal dynamic in mice destabilizes their memory of fear conditioning.

Engrams in amygdala lean on astrocytes to solidify memories
Disrupting the astrocyte-neuronal dynamic in mice destabilizes their memory of fear conditioning.