Timothy O’Leary.

Timothy O’Leary

Professor of information engineering and neuroscience
University of Cambridge

Timothy O’Leary is professor of information engineering and neuroscience at the University of Cambridge. His research lies at the intersection between physiology, computation and control engineering. His goal is to understand how nervous systems self-organize, adapt and fail, and to connect these to diversity and variability in nervous system properties.

Originally trained as a pure mathematician, O’Leary dropped out of a Ph.D. on hyperbolic geometry to study the brain. After retraining as an experimental physiologist, he obtained his doctorate in experimental and computational neuroscience from the University of Edinburgh in 2009.

He has worked as both an experimentalist and theoretician, on systems that span the scale from single ion channel dynamics to whole brain and behavior, and across invertebrate and vertebrate species. His group works closely with experimentalists to study neuromodulation, neural dynamics and how sensorimotor information is represented in the brain, more recently focusing on how neural representations evolve over time. He approaches these problems from an unusual perspective, citing engineering principles as being key to understanding the brain—and biology more widely.

From this contributor

Explore more from The Transmitter

Gerry Fischbach at a podium.

Remembering Gerry Fischbach, ‘orchestra conductor’ who brought scientists together

Fischbach, who died 25 October, elucidated the dynamic changes in neuromuscular junctions. Beyond the lab, he shaped careers, academic departments and scientific societies.

By Claudia López Lloreda
29 October 2026 | 8 min read
Mouse wearing a white, cube-like device on its head.

WILD platform levels up ability to record brain activity, behavior in nature

The customizable rig combines multimodal recording, onboard processing and neuronal manipulation to power more complex experiments.

By Simon Makin
29 October 2026 | 6 min read

The relationship between structure and function in cortical networks

Michael Reimann explains how the shape of neurons puts strong constraints on how they are wired in a network, and how this affects their structure-function relationships.

By Gaute Einevoll
28 October 2026 | 138 min listen