Cortex

Recent articles

A cortical neuron glows orange and red.

START method assembles brain’s wiring diagram by cell type

The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.

By Holly Barker
31 October 2024 | 5 min read
Research image of tau proteins in the brains of people with Alzheimer’s disease.

Supersized version of Alzheimer’s protein avoids clumping in brain

“Big tau” may explain why some brain regions, such as the cerebellum and brainstem, are largely spared from neurodegeneration, even though tau is expressed throughout the nervous system.

By Charles Q. Choi
16 August 2024 | 6 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
Research image of fetal macaque brains.

Brain patterning in utero may be implicated in autism, other conditions

Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.

By Chloe Williams
1 August 2024 | 6 min read
A marble bust of a face that is covered in real leaves.

Newly found circuit through visual cortex powers first look at faces

The superior colliculus, an evolutionarily ancient brain area responsible for eye movements, responds to faces before the canonical face areas do, a study of macaque monkeys suggests.

By Olivia Gieger
19 July 2024 | 5 min read
A photograph of Paul-Antoine Libourel.

At the end of the earth with Paul-Antoine Libourel

The French researcher’s accomplishments working with chinstrap penguins in the Antarctic highlight the importance of recording sleep in the wild.

By Yves Sciama
11 June 2024 | 18 min listen
Illustration of a yellow brain and a pink brain

Monkey studies throw wrench into decade-old idea about movement’s effect on visual cortex

Movements that boost activity in the visual cortex of mice have the opposite or no effect in marmosets and macaques, prompting questions about whether mice are a suitable model for the primate visual system.

By Angie Voyles Askham
20 February 2024 | 9 min read
Two hands hold a mouse.

Noisy brain may underlie some of autism’s sensory features

Random fluctuations in neuronal activity are more variable in a fragile X mouse model than in wildtype mice.

By Holly Barker
18 January 2024 | 6 min read
Research images of the human motor cortex

What happens when a histopathologist teams up with computational modelers?

Answers emerge in my chat with Nicola Palomero-Gallagher, a rare example of someone who connects the brain’s microscopic constituents and macroscopic features.

By Mac Shine
11 December 2023 | 7 min read
Research image of various types of cells.

Vast diversity of human brain cell types revealed in trove of new datasets

The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.

By Angie Voyles Askham
12 October 2023 | 7 min listen

Explore more from The Transmitter

Illustration of a brain overlaid with circles containing flowers and circuit-like networks, among other images.

NeuroAI: A field born from the symbiosis between neuroscience, AI

As the history of this nascent discipline reveals, neuroscience has inspired advances in artificial intelligence, and AI has provided a testing ground for models in neuroscience, accelerating progress in both fields.

By Anthony Zador
11 November 2024 | 6 min read
Illustration of a simple matrix of overlapping circles next to a more complex network of intersecting lines against a muted but colorful background.

What the brain can teach artificial neural networks

The brain offers valuable lessons to artificial neural networks to boost their data and energy efficiency, flexibility and more.

By Anthony Zador
11 November 2024 | 7 min read
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How Anthony Zador thinks neuroscience can help improve AI

Artificial intelligence is ubiquitous and powerful, but can neuroscience still help advance it? Zador describes the “virtuous circle” of neuroscience and AI that drives progress in both fields.

By Paul Middlebrooks
11 November 2024 | 93 min listen