MRI

Illustration of hands organizing objects of various shapes and sizes.

Simply making data publicly available isn’t enough. We need to make it easy — that requires community buy-in.

I helped create a standard to make it easy to upload, analyze and compare functional MRI data. An ecosystem of tools has since grown up around it, boosting reproducibility and speeding up research.

By Russell Poldrack
17 January 2024 | 7 min read
Research images of the human motor cortex

What happens when a histopathologist teams up with computational modelers?

Answers emerge in my chat with Nicola Palomero-Gallagher, a rare example of someone who connects the brain’s microscopic constituents and macroscopic features.

By Mac Shine
11 December 2023 | 7 min read
Brain imaging Microphone

Common genetic variants shape the structure of the cortex

A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.

By Lauren Schenkman
18 September 2023 | 5 min listen
Research image of brain scans displaying gray-matter volume differences across across six psychiatric conditions.
Circuits Microphone

Alterations in circuits characterize six neuropsychiatric conditions

The underlying regional neurobiology of the conditions may differ from person to person.

By Claudia López Lloreda
13 September 2023 | 4 min listen
A grid of four brain scans showing excess cerebrospinal fluid.
Spectrum Microphone

Is excess brain fluid an early marker of autism?

Brain scans of hundreds of infants suggest that up to 80 percent of those with autism have unusual amounts of cerebrospinal fluid. Researchers are studying how this might contribute to the condition.

By Giorgia Guglielmi
17 August 2023 | 10 min read
Research image of neurons.

Abundant motor proteins disrupt cries in FOXP2 mice

Knocking down the gene that codes for the proteins normalizes the vocalizations.

By Laura Dattaro, Maaisha Osman
28 July 2023 | 3 min read
Research image of brain scans showing connections in the brain in different colors.

Statistical method improves behavioral predictions from fMRI

The framework, inspired by the polygenic risk score, considers the cumulative effect of neuronal connections.

By Holly Barker
29 June 2023 | 4 min read
Illustration of a watch with the face taken up by an MRI scan of a brain.

Ruth Carper: Imaging the aging brain in autistic adults

Few studies have tracked how brain structure and function change across adulthood in people with autism. Carper and her colleagues are collecting data to fill this gap.

By Peter Hess
19 May 2023 | 7 min read
Illustration of a brain.

Cortical differences in autism vary by sex

Compared with their non-autistic peers, young autistic girls have a thicker cortex that thins more quickly with age.

By Giorgia Guglielmi
4 May 2023 | 2 min read
MRI scan with a section enlarged to display the scan's grey-white boundary.
Brain imaging Microphone

Brain imaging do-over offers clues to field’s replication problem

Methodological choices and study-site artifacts confounded an attempt to replicate findings in support of an autism brain-imaging biomarker, according to new unpublished work.

By Angie Voyles Askham
13 March 2023 | 6 min listen

Explore more from The Transmitter

Brain organoid size matches intensity of social problems in autistic people

Overgrown organoids could point to mechanisms underlying profound autism.

By Holly Barker
18 July 2024 | 5 min read

Persistent protein pairing enables memories to last

The complex of two memory proteins, rather than the individual molecules acting independently, underlie month-long memories in mice, a new study suggests.

By Elissa Welle
17 July 2024 | 5 min read
A digitally distorted image of a file folder against a blue gradient background.

Data access changes to UK Biobank stir unease in neuroscientists

“I feel a little bit in limbo,” says neuroscientist Stephanie Noble, who has paused a study using Biobank data after the repository shifted from a data download to a cloud-only access model.

By Calli McMurray
16 July 2024 | 7 min read