Neurogenesis

Recent articles

Research image of portions of the adult dentate gyrus.

Machine learning spots neural progenitors in adult human brains

But the finding has not settled the long-standing debate over the existence and extent of neurogenesis during adulthood, says Yale University neuroscientist Juan Arellano.

By Claudia López Lloreda
3 July 2025 | 7 min listen
A research image of autism-linked genes.

Autism-linked perturbations converge on cell skeleton and RNA-binding proteins

The findings solidify the idea that autism-linked mutations affect brain activity by way of several key shared mechanisms.

By Giorgia Guglielmi
29 February 2024 | 4 min read
Research image of organoids in the forebrain.

Head size parts autism into two major subtypes

An imbalance in the number of excitatory neurons in early brain development may account for the difference.

By Charles Q. Choi
12 September 2023 | 4 min read
Composite research image of organoids at several stages of development.

Genetic background sways effects of autism-linked mutation

Experiments offer clues to why certain mutations are associated with autism in some people and not others.

By Charles Q. Choi
18 May 2023 | 4 min read
Research image of the blood-brain barrier.

Rare autism-linked mutation starves growing neurons of essential nutrients

The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.

By Lauren Schenkman
10 April 2023 | 5 min read
Research image of radial glial cells in a human brain organoid.

Immune molecule alters cellular makeup of human brain organoids

The changes may help explain the link between maternal infection and autism, though more research is needed.

By Charles Q. Choi
5 April 2023 | 5 min listen
Research image shows elevated expression of certain genes, shown in pink and green, along with expected gene expression, shown in blue.

Autism-linked MYT1L mutations prompt ‘identity crisis’ in budding brain cells

Both human and mouse progenitor cells with the alterations struggle to become neurons and instead express genes that are typically active only in muscle or the heart.

By Laura Dattaro
14 February 2023 | 5 min read
Research image comparing neurons that lack the ZFP462 gene to wildtype neurons.

Autism-tied gene ZNF462 keeps developing neurons on track

The gene, linked to a little-known condition called Weiss-Kruszka syndrome, prevents embryonic stem cells from deviating from their neuronal destiny.

By Laura Dattaro
1 February 2023 | 4 min read
Image of a synthetic mouse embryo.

Lab-grown ‘embryoids’ offer new window into gene-trait relationships

The developmental models have advantages over natural embryos and other synthetic models, such as organoids, but present technical and ethical challenges.

By Isabel Ruehl
26 October 2022 | 4 min read

Explore more from The Transmitter

Research image of neural activity in mouse auditory cortices.

Rise in autism prevalence but not traits; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 7 July.

By Jill Adams
8 July 2025 | 2 min read
A fly over a background of waves of different colors.

Drosophila, like vertebrates, filter sensory information during sleep

Predictive sensory processing in sleeping Drosophila echoes vertebrate research, establishing an evolutionarily conserved neural signature of sleep.

By Siddhant Pusdekar
8 July 2025 | 5 min listen
Two researchers wander through stacks of pie charts.

Neuroscience’s open-data revolution is just getting started

Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments. New tools that make open data easier to use—and new pressures, including funding cuts—may increase uptake.

By Benjamin Dichter
7 July 2025 | 8 min listen