Organoids

Recent articles

Research image showing gene association.

Organoid study reveals shared brain pathways across autism-linked variants

The genetic variants initially affect brain development in unique ways, but over time they converge on common molecular pathways.

By Giorgia Guglielmi
19 February 2026 | 4 min read
Chimpanzee neural organoid.

Viral remnant in chimpanzees silences brain gene humans still use

The retroviral insert appears to inadvertently switch off a gene involved in brain development.

By Siddhant Pusdekar
27 January 2026 | 5 min read
Research image of stem cells derived from people of African ancestry.

Bringing African ancestry into cellular neuroscience

Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.

By Lauren Schenkman
14 January 2026 | 7 min read
Research image of organoids derived from stem cell lines from people with intellectual disability, polymicroglia or microcephaly, alongside a control organoid.

New organoid atlas unveils four neurodevelopmental signatures

The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.

By Diana Kwon
17 December 2025 | 4 min read
Brain organoid.

What is the future of organoid and assembloid regulation?

Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.

By Claudia López Lloreda
10 December 2025 | 7 min read
Concentric circles.

What are the most transformative neuroscience tools and technologies developed in the past five years?

Artificial intelligence and deep-learning methods featured prominently in the survey responses, followed by genetic tools to control circuits, advanced neuroimaging, transcriptomics and various approaches to record brain activity and behavior.

By The Transmitter
15 November 2025 | 14 min read
Colorful drawing of a human brain.

‘Neuroethics: The Implications of Mapping and Changing the Brain,’ an excerpt

In his new book, published today, philosopher Walter Glannon examines the ethics of six areas of neuroscience. In Chapter 4, a portion of which appears below, he tackles the ethical considerations of using brain organoids in research.

By Walter Glannon
11 November 2025 | 7 min read
Research image of microglia in organoids.

Microglia nurture young interneurons

The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”

By Lauren Schenkman
28 August 2025 | 3 min read
Researcher holds a mouse perched on a glass cylinder.

NIH proposal sows concerns over future of animal research, unnecessary costs

The new NIH policy calls for greater incorporation of new approach methodologies in all future Notices of Funding Opportunities related to animal model systems.

By Claudia López Lloreda
15 July 2025 | 5 min read
Composite image of a brain probe, a test tube and a brain scan.

Why the 21st-century neuroscientist needs to be neuroethically engaged

Technological advances in decoding brain activity and in growing human brain cells raise new ethical issues. Here is a framework to help researchers navigate them.

By Karen Rommelfanger
12 May 2025 | 6 min read

Explore more from The Transmitter

Tick on a leaf raises its forelegs.

Neuro’s ark: Spying on the secret sensory world of ticks

Carola Städele, a self-proclaimed “tick magnet,” studies the arachnids’ sensory neurobiology—in other words, how these tiny parasites zero in on their next meal.

By Calli McMurray
3 March 2026 | 6 min read
Research image of mice brains.

Autism in old age, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 2 March.

By Jill Adams
3 March 2026 | 1 min read
Sheet of paper with a red pencil struck through it.

Lack of reviewers threatens robustness of neuroscience literature

Simple math suggests that small groups of scientists can significantly bias peer review.

By Jakob Voigts
2 March 2026 | 14 min read

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