Almost every human cell teems with a potpourri of tiny powerhouses: mitochondria. Up to thousands of them. These organelles use oxygen to convert the nutrients from the food you eat into a form of energy the body can use. The brain consumes a lot of this energy — about 20 percent. Could changes in mitochondria, then, affect how the brain functions and contribute to autism? Read the related article, Meet the ‘mitomaniacs’ who say mitochondria matter in autism.
Mitochondria: An energy explanation for autism
People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.
By
Laura Dattaro
22 November 2021 | 3 min watch
Illustration by Mengxin Li
Recommended reading

Gene-activity map of developing brain reveals new clues about autism’s sex bias
By
Giorgia Guglielmi
16 October 2025 | 6 min listen

Parsing phenotypes in people with shared autism-linked variants; and more
By
Jill Adams
14 October 2025 | 2 min read

Boosting SCN2A expression reduces seizures in mice
By
Charles Q. Choi
9 October 2025 | 5 min read
Explore more from The Transmitter

Fly database secures funding for another year, but future remains in flux
By
Calli McMurray
17 October 2025 | 3 min read

Diving in with Nachum Ulanovsky
By
Claudia López Lloreda
16 October 2025 | 14 min listen

Engrams in amygdala lean on astrocytes to solidify memories
By
Lauren Schneider
15 October 2025 | 6 min listen
Cite this article: