Stem cells
Recent articles
Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”
Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”
Why hype for autism stem cell therapies continues despite dead ends
After numerous tests, there is still no evidence that these experimental treatments help, so now is not the time to expand access to them.
Why hype for autism stem cell therapies continues despite dead ends
After numerous tests, there is still no evidence that these experimental treatments help, so now is not the time to expand access to them.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain
Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.
In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain
Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.
Organoids and assembloids offer a new window into human brain
These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.
Organoids and assembloids offer a new window into human brain
These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.
Impaired molecular ‘chaperone’ accompanies multiple brain changes, conditions
Rare genetic variants in a protein-folding complex contribute to a spectrum of phenotypes that encompass brain malformations, intellectual disability, autism and seizures, according to a new “hallmark” study.
Impaired molecular ‘chaperone’ accompanies multiple brain changes, conditions
Rare genetic variants in a protein-folding complex contribute to a spectrum of phenotypes that encompass brain malformations, intellectual disability, autism and seizures, according to a new “hallmark” study.
Brain organoid size matches intensity of social problems in autistic people
Overgrown organoids could point to mechanisms underlying profound autism.
Brain organoid size matches intensity of social problems in autistic people
Overgrown organoids could point to mechanisms underlying profound autism.
Autism subgroups converge on cell growth pathway
Faulty mTOR signaling, implicated in syndromic forms of autism, also hinders cells grown from people with idiopathic autism or autism-linked deletions on chromosome 16.
Autism subgroups converge on cell growth pathway
Faulty mTOR signaling, implicated in syndromic forms of autism, also hinders cells grown from people with idiopathic autism or autism-linked deletions on chromosome 16.
Building a brain: How does it generate its exquisite diversity of cells?
High-throughput technologies have revealed new insights into how the brain develops. But a truly comprehensive map of neurodevelopment requires further advances.
Building a brain: How does it generate its exquisite diversity of cells?
High-throughput technologies have revealed new insights into how the brain develops. But a truly comprehensive map of neurodevelopment requires further advances.
Raising the bar for stem cell research: Q&A with Jack Mosher
New quality benchmarks for basic research involving stem cells promise to improve rigor and reproducibility, says Mosher, who helped develop the standards.
Raising the bar for stem cell research: Q&A with Jack Mosher
New quality benchmarks for basic research involving stem cells promise to improve rigor and reproducibility, says Mosher, who helped develop the standards.
Explore more from The Transmitter
How will neuroscience training need to change in the future?
Training in computational neuroscience, data science and statistics will need to expand, say many of the scientists we surveyed. But that must be balanced with a more traditional grounding in the scientific method and critical thinking. Researchers noted that funding concerns will also affect training, especially for people from underrepresented groups.
How will neuroscience training need to change in the future?
Training in computational neuroscience, data science and statistics will need to expand, say many of the scientists we surveyed. But that must be balanced with a more traditional grounding in the scientific method and critical thinking. Researchers noted that funding concerns will also affect training, especially for people from underrepresented groups.
The leaders we have lost
Learn more about the lives and legacies of the neuroscientists who passed away between 2023 and 2025.
The leaders we have lost
Learn more about the lives and legacies of the neuroscientists who passed away between 2023 and 2025.
What are the most-cited neuroscience papers from the past 30 years?
Highly cited papers reflect the surge in artificial-intelligence research in the field and other technical advances, plus prizewinning work on analgesics, the fusiform face area and ion channels.
What are the most-cited neuroscience papers from the past 30 years?
Highly cited papers reflect the surge in artificial-intelligence research in the field and other technical advances, plus prizewinning work on analgesics, the fusiform face area and ion channels.