Striatum

Recent articles

Research image of mouse brain slices.

Some dopamine neurons signal default behaviors to reinforce habits

Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

By Holly Barker
11 June 2025 | 5 min listen
Research image showing resting-state functional connectivity in the human red nucleus.

‘Ancient’ brainstem structure evolved beyond basic motor control

The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.

By Sydney Wyatt
16 May 2025 | 5 min read
Child playing with blocks.

Structure of striatum varies by sex in autistic children

The changes could reflect different developmental trajectories between boys and girls with autism, a new study suggests.

By Holly Barker
27 February 2025 | 4 min read
Research image of circuits emerging from striosomes in the striatum.

Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control

The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.

By Claudia López Lloreda
24 January 2025 | 4 min read
Illustration of cranes attempting to assemble a structure out of very small black squares.

Reconstructing dopamine’s link to reward

The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.

By Angie Voyles Askham
13 September 2024 | 20 min listen
Research image of neurons in mice.

Skewed signaling in striatum may spawn repetitive behaviors

Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.

By Holly Barker
6 September 2023 | 3 min read
Research image of neurons.

Abundant motor proteins disrupt cries in FOXP2 mice

Knocking down the gene that codes for the proteins normalizes the vocalizations.

By Laura Dattaro, Maaisha Osman
28 July 2023 | 3 min read

Autism’s ties to the cell skeleton

Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.

By Giorgia Guglielmi
22 June 2023 | 7 min read
Composite image of inhibitory and excitatory neurons.

One-rosette technique grows well-organized organoids

The method yields complex organoids that more closely mimic embryonic brain development than do those cultured in other ways.

By Peter Hess
2 December 2022 | 5 min listen
Mouse brain slices showing the effects of SHANK2 and SHANK3 deletions.

Double SHANK knockout highlights brain circuit’s social role

Mice missing the autism-linked SHANK2 and SHANK3 genes in their retrosplenial cortex have trouble distinguishing between novel and familiar mice.

By Angie Voyles Askham
19 October 2022 | 5 min read

Explore more from The Transmitter

INSAR takes ‘intentional break’ from annual summer webinar series

The International Society for Autism Research cited a need to “thoughtfully reimagine” its popular online program before resuming it in 2026.

By Lauren Schenkman
30 June 2025 | 4 min read
Research image showing that activity in single neurons spikes when a person encodes sequential items into working memory.

Null and Noteworthy: Neurons tracking sequences don’t fire in order

Instead, neurons encode the position of sequential items in working memory based on when they fire during ongoing brain wave oscillations—a finding that challenges a long-standing theory.

By Laura Dattaro
30 June 2025 | 4 min read
A hand points to a chalkboard with an astrocyte on it.

How to teach this paper: ‘Neurotoxic reactive astrocytes are induced by activated microglia,’ by Liddelow et al. (2017)

Shane Liddelow and his collaborators identified the factors that transform astrocytes from their helpful to harmful form. Their work is a great choice if you want to teach students about glial cell types, cell culture, gene expression or protein measurement.

By Ashley Juavinett
30 June 2025 | 10 min read