GWAS
Recent articles
Revised statistical bar extracts less-common variants from autism genetics studies
Adjusting genetic analyses could help plug autism’s heritability gap, according to a new preprint.
Revised statistical bar extracts less-common variants from autism genetics studies
Adjusting genetic analyses could help plug autism’s heritability gap, according to a new preprint.
Common and rare variants shape distinct genetic architecture of autism in African Americans
Certain gene variants may have greater weight in determining autism likelihood for some populations, a new study shows.
Common and rare variants shape distinct genetic architecture of autism in African Americans
Certain gene variants may have greater weight in determining autism likelihood for some populations, a new study shows.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Genetic profiles separate early, late autism diagnoses
Age at diagnosis reflects underlying differences in common genetic variants and developmental trajectories among people with autism.
Genetic profiles separate early, late autism diagnoses
Age at diagnosis reflects underlying differences in common genetic variants and developmental trajectories among people with autism.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Sequencing study spotlights tight web of genes tied to autism
The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.
Sequencing study spotlights tight web of genes tied to autism
The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.
New catalog charts familial ties from autism to 90 other conditions
The research tool reveals associations stretching across three generations.
New catalog charts familial ties from autism to 90 other conditions
The research tool reveals associations stretching across three generations.
Breaking down the winner’s curse: Lessons from brain-wide association studies
We found an issue with a specific type of brain imaging study and tried to share it with the field. Then the backlash began.
Breaking down the winner’s curse: Lessons from brain-wide association studies
We found an issue with a specific type of brain imaging study and tried to share it with the field. Then the backlash began.
Common genetic variants shape the structure of the cortex
A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.
Common genetic variants shape the structure of the cortex
A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.
Atlas of gene activity in prenatal brain holds clues to autism
Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.
Atlas of gene activity in prenatal brain holds clues to autism
Genes exert their strongest influence on the brain in the first half of gestation — a key window for autism and other neurodevelopmental conditions.
Explore more from The Transmitter
Remembering Annette Dolphin, who helped explain gabapentin’s effects
The "intuitive" neuropharmacologist pushed against the status quo.
Remembering Annette Dolphin, who helped explain gabapentin’s effects
The "intuitive" neuropharmacologist pushed against the status quo.
Tom Griffiths describes how neural networks, logic and probability theory together explain cognition
In his new book, “The Laws of Thought,” Griffiths shows how these three pillars of study complement one another and together form a solid foundation to eventually explain all of our cognition, from brain to mind.
Tom Griffiths describes how neural networks, logic and probability theory together explain cognition
In his new book, “The Laws of Thought,” Griffiths shows how these three pillars of study complement one another and together form a solid foundation to eventually explain all of our cognition, from brain to mind.
This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments
In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological properties. The work inspired Lerner to think about how to challenge widely held assumptions in the field.
This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments
In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological properties. The work inspired Lerner to think about how to challenge widely held assumptions in the field.