Hypothalamus

Recent articles

Research image of grids of mouse and human brain scans.

Too much or too little brain synchrony may underlie autism subtypes

Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.

By Calli McMurray
17 April 2025 | 6 min read
Two mice sleeping.

Soft touch quells loneliness in mice

Touch modulates one of two dueling types of hypothalamic neurons that, thermostat-like, balance an animal’s drive for social interaction.

By Angie Voyles Askham
26 February 2025 | 6 min read
Research image of gene expression in cells in the third ventricle of the hypothalamus of young and aged mice.

Age-related brain changes in mice strike hypothalamus ‘hot spot’

Neuronal and non-neuronal cells throughout the brain also express genes—particularly those related to neuronal structure and immune function—differently in aged mice, according to a new atlas.

By Angie Voyles Askham
8 January 2025 | 6 min listen
Illustration of a mouse melting in front of a fan.

To beat the heat, hypothalamus neurons in mice ramp up their firing

The uptick may help the rodents acclimate to temperature hikes and keep their cool.

By Calli McMurray
11 December 2024 | 7 min read
Research image of brain circuits.

Novel neurons upend ‘yin-yang’ model of hunger, satiety in brain

The new type of leptin-sensitive cells curb hunger quickly—adding to an increasingly complex picture of brain circuits that control feeding behaviors.

By Giorgia Guglielmi
9 December 2024 | 5 min read
A squirrel sleeps on the ground with its toe in its mouth.

Rousing a ‘new era’ of hibernation research

Novel applications of neuroscience tools have enabled researchers to uncover the neural controls of an extreme biological trait.

By Shaena Montanari
8 November 2024 | 9 min read
Illustration of a mouse with cheese on its left and a drop of water on its right.

Should I stay (and eat) or should I go? How the brain balances hunger with competing drives

Understanding the interplay among rival signals, such as pain, thirst and fear, could provide insights into anxiety and other neuropsychiatric conditions.

By Giorgia Guglielmi
11 October 2024 | 8 min read
A man walks a dromedary camel down an outdoor walkway.

Temperature tunes circadian timing in some desert mammals

Light has hogged all the attention in chronobiology research—but now, in camel, goat and mole rat experiments, temperature takes the lead.

By Calli McMurray
28 June 2024 | 5 min read
Photograph of an intimidating lab mouse.

Newly found hypothalamus circuits shape bullying behaviors in mice

Activity in the tiny brain region helps submissive rodents learn to avoid aggressors, and aggressive mice to curb their attacks, according to two recent studies.

By Angie Voyles Askham
5 March 2024 | 6 min listen
Scanning elecgron micrograph of Faecal bacteria.

Gut microbes shape social behavior in autism mouse model

Treating mice missing the autism-linked gene CNTNAP2 with a strain of gut bacteria makes them more social but no less hyperactive.

By Angie Voyles Askham
26 March 2021 | 4 min read

Explore more from The Transmitter

Research image of neuron organization in c elegans.

Worms help untangle brain structure/function mystery

The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans

By Holly Barker
29 August 2025 | 7 min read
Research image of microglia in organoids.

Microglia nurture young interneurons

The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”

By Lauren Schenkman
28 August 2025 | 4 min read

Xaq Pitkow shares his principles for studying cognition in our imperfect brains and bodies

Pitkow discusses how evolution's messy constraints shape optimal brain algorithms, from Bayesian inference to ecological affordances.

By Paul Middlebrooks
27 August 2025 | 1 min read

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