SFN 2022
Recent articles
Single gene insufficient to account for dup15q, Angelman traits
UBE3A, a key gene associated with both autism-linked conditions, can explain most — but not all — of the syndromes’ atypical neuronal properties.
Single gene insufficient to account for dup15q, Angelman traits
UBE3A, a key gene associated with both autism-linked conditions, can explain most — but not all — of the syndromes’ atypical neuronal properties.
Excess of ‘don’t eat me’ cell signals may drive brain enlargement in autism
The signal, called CD47, is disrupted in autistic people who have a larger-than-average head.

Excess of ‘don’t eat me’ cell signals may drive brain enlargement in autism
The signal, called CD47, is disrupted in autistic people who have a larger-than-average head.
Autism’s sex bias tied to glial, immune cell gene expression
The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.

Autism’s sex bias tied to glial, immune cell gene expression
The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.
Shared brain structure, connectivity hint at autism subgroups
Using imaging methods to sort mouse models of autism may help identify subtypes of autistic people with similar underlying biology.

Shared brain structure, connectivity hint at autism subgroups
Using imaging methods to sort mouse models of autism may help identify subtypes of autistic people with similar underlying biology.
Organoids identify potential therapies, circuit flaws for autism-linked syndromes
Brain cell clusters serve as drug screens and reveal connectivity differences for autism-linked conditions, two new models show.

Organoids identify potential therapies, circuit flaws for autism-linked syndromes
Brain cell clusters serve as drug screens and reveal connectivity differences for autism-linked conditions, two new models show.
Subtyping autism using fMRI: A quick take at SfN with Marco Pagani
Pagani used mouse models to connect autism etiologies to brain connectivity alterations and then found similar alterations in people with idiopathic forms of the condition.
Subtyping autism using fMRI: A quick take at SfN with Marco Pagani
Pagani used mouse models to connect autism etiologies to brain connectivity alterations and then found similar alterations in people with idiopathic forms of the condition.
Zebrafish social behavior swims into mainstream
New studies bolster the idea that zebrafish models can say something meaningful about social behavior in autism.
Zebrafish social behavior swims into mainstream
New studies bolster the idea that zebrafish models can say something meaningful about social behavior in autism.
Brain’s memory center flags autistic adults at risk for cognitive decline
Brain scans of the hippocampus reveal autistic people who are at increased risk of cognitive problems as they get older.

Brain’s memory center flags autistic adults at risk for cognitive decline
Brain scans of the hippocampus reveal autistic people who are at increased risk of cognitive problems as they get older.
Autism genes converge on disruptions in social brain circuit
The circuit linking the prefrontal cortex and part of the thalamus is impaired in mice raised in social isolation and in mice with mutations in the FMR1 or TSC2 genes.

Autism genes converge on disruptions in social brain circuit
The circuit linking the prefrontal cortex and part of the thalamus is impaired in mice raised in social isolation and in mice with mutations in the FMR1 or TSC2 genes.
Screening zebrafish autism models: A quick take at SfN with Ellen Hoffman
Zebrafish with mutations in 10 different autism-linked genes show a range of unique and shared phenotypes.
Screening zebrafish autism models: A quick take at SfN with Ellen Hoffman
Zebrafish with mutations in 10 different autism-linked genes show a range of unique and shared phenotypes.
Explore more from The Transmitter
‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt
In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community's "Grand Plan."

‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt
In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community's "Grand Plan."
Convergent effects of autism-linked genes in zebrafish; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 9 June.

Convergent effects of autism-linked genes in zebrafish; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 9 June.
More than two dozen papers by neural tube researcher come under scrutiny
One of the studies, published in 2021 in Science Advances, received an editorial expression of concern on 21 May, after the journal learned that an institutional review of alleged image problems is underway.

More than two dozen papers by neural tube researcher come under scrutiny
One of the studies, published in 2021 in Science Advances, received an editorial expression of concern on 21 May, after the journal learned that an institutional review of alleged image problems is underway.