Striatum

Recent articles

Research image of mouse brain slices.

Some dopamine neurons signal default behaviors to reinforce habits

Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

By Holly Barker
11 June 2025 | 5 min listen
Research image showing resting-state functional connectivity in the human red nucleus.

‘Ancient’ brainstem structure evolved beyond basic motor control

The human red nucleus may also help coordinate action, reward and motivated behavior, a new study suggests.

By Sydney Wyatt
16 May 2025 | 5 min read
Child playing with blocks.

Structure of striatum varies by sex in autistic children

The changes could reflect different developmental trajectories between boys and girls with autism, a new study suggests.

By Holly Barker
27 February 2025 | 4 min read
Research image of circuits emerging from striosomes in the striatum.

Newly characterized striatal circuits add twist to ‘go/no-go’ model of movement control

The two novel pathways control dopamine release in opposing ways and may link motivation and mood to action, a new study shows.

By Claudia López Lloreda
24 January 2025 | 4 min read
Illustration of cranes attempting to assemble a structure out of very small black squares.

Reconstructing dopamine’s link to reward

The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.

By Angie Voyles Askham
13 September 2024 | 20 min listen
Research image of neurons in mice.

Skewed signaling in striatum may spawn repetitive behaviors

Synaptic changes in the brain region could drive a core trait of fragile X syndrome, a new mouse study suggests.

By Holly Barker
6 September 2023 | 3 min read
Research image of neurons.

Abundant motor proteins disrupt cries in FOXP2 mice

Knocking down the gene that codes for the proteins normalizes the vocalizations.

By Laura Dattaro, Maaisha Osman
28 July 2023 | 3 min read

Autism’s ties to the cell skeleton

Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.

By Giorgia Guglielmi
22 June 2023 | 7 min read
Composite image of inhibitory and excitatory neurons.

One-rosette technique grows well-organized organoids

The method yields complex organoids that more closely mimic embryonic brain development than do those cultured in other ways.

By Peter Hess
2 December 2022 | 5 min listen
Mouse brain slices showing the effects of SHANK2 and SHANK3 deletions.

Double SHANK knockout highlights brain circuit’s social role

Mice missing the autism-linked SHANK2 and SHANK3 genes in their retrosplenial cortex have trouble distinguishing between novel and familiar mice.

By Angie Voyles Askham
19 October 2022 | 5 min read

Explore more from The Transmitter

Two researchers wander through stacks of pie charts.

Neuroscience’s open-data revolution is just getting started

Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments. New tools that make open data easier to use—and new pressures, including funding cuts—may increase uptake.

By Benjamin Dichter
7 July 2025 | 6 min read
Research image of portions of the adult dentate gyrus.

Machine learning spots neural progenitors in adult human brains

But the finding has not settled the long-standing debate over the existence and extent of neurogenesis during adulthood, says Yale University neuroscientist Juan Arellano.

By Claudia López Lloreda
3 July 2025 | 7 min listen

Xiao-Jing Wang outlines the future of theoretical neuroscience

Wang discusses why he decided the time was right for a new theoretical neuroscience textbook and how bifurcation is a key missing concept in neuroscience explanations.

By Paul Middlebrooks
2 July 2025 | 112 min listen