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Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission
Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”
Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission
Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
How microscopic ‘condensates’ in cells might contribute to autism
A controversial idea about how cells compartmentalize their contents into droplets — like beads of oil in water — could be key to understanding autism, says Julie Forman-Kay.
How microscopic ‘condensates’ in cells might contribute to autism
A controversial idea about how cells compartmentalize their contents into droplets — like beads of oil in water — could be key to understanding autism, says Julie Forman-Kay.
New method exposes structures inside ‘rainbow’ of brain cells
Molecules from alpacas may enable scientists to identify cell types in the brain while also revealing their interior structures.
New method exposes structures inside ‘rainbow’ of brain cells
Molecules from alpacas may enable scientists to identify cell types in the brain while also revealing their interior structures.
Dividing autism; novel messengers; million-dollar mark and more
A researcher proposes splitting autism into subtypes, mitochondria make neurotransmitters, and highly successful grantees may face a funding cap.
Dividing autism; novel messengers; million-dollar mark and more
A researcher proposes splitting autism into subtypes, mitochondria make neurotransmitters, and highly successful grantees may face a funding cap.
New tool spotlights neuron junctions in living human brains
A new imaging technique allows researchers to illuminate the junctions between neurons in a living person’s brain.
New tool spotlights neuron junctions in living human brains
A new imaging technique allows researchers to illuminate the junctions between neurons in a living person’s brain.
Rainbow of dyes maps neurons’ tangled paths in brain
A new method that lets researchers trace the paths of many neurons at once may reveal how neurons go astray in autism.
Rainbow of dyes maps neurons’ tangled paths in brain
A new method that lets researchers trace the paths of many neurons at once may reveal how neurons go astray in autism.
Suite of methods yields complex model of neuronal junctions
Researchers debuted a three-dimensional model of an average synapse, the point of connection between neurons, in the 30 May issue of Science.
Suite of methods yields complex model of neuronal junctions
Researchers debuted a three-dimensional model of an average synapse, the point of connection between neurons, in the 30 May issue of Science.
Molecular mechanisms: Autism gene establishes brain links
The autism-linked protein MET is expressed at the junctions between neurons during early brain development in mice, suggesting that it helps establish the connections, according to a study published 21 June in The Journal of Comparative Neurology.
Molecular mechanisms: Autism gene establishes brain links
The autism-linked protein MET is expressed at the junctions between neurons during early brain development in mice, suggesting that it helps establish the connections, according to a study published 21 June in The Journal of Comparative Neurology.
Researchers watch as proteins travel to neuronal junctions
Using high-resolution microscopy, researchers can watch as signaling complexes assemble at neuronal junctions in zebrafish embryos, according to a study published 17 April in Cell Reports.
Researchers watch as proteins travel to neuronal junctions
Using high-resolution microscopy, researchers can watch as signaling complexes assemble at neuronal junctions in zebrafish embryos, according to a study published 17 April in Cell Reports.
Explore more from The Transmitter
Null and Noteworthy: Neurons tracking sequences don’t fire in order
Instead, neurons encode the position of sequential items in working memory based on when they fire during ongoing brain wave oscillations—a finding that challenges a long-standing theory.
Null and Noteworthy: Neurons tracking sequences don’t fire in order
Instead, neurons encode the position of sequential items in working memory based on when they fire during ongoing brain wave oscillations—a finding that challenges a long-standing theory.
How to teach this paper: ‘Neurotoxic reactive astrocytes are induced by activated microglia,’ by Liddelow et al. (2017)
Shane Liddelow and his collaborators identified the factors that transform astrocytes from their helpful to harmful form. Their work is a great choice if you want to teach students about glial cell types, cell culture, gene expression or protein measurement.
How to teach this paper: ‘Neurotoxic reactive astrocytes are induced by activated microglia,’ by Liddelow et al. (2017)
Shane Liddelow and his collaborators identified the factors that transform astrocytes from their helpful to harmful form. Their work is a great choice if you want to teach students about glial cell types, cell culture, gene expression or protein measurement.
Astrocytes sense neuromodulators to orchestrate neuronal activity and shape behavior
Astrocytes serve as crucial mediators of neuromodulatory processes previously attributed to direct communication between neurons, four new studies show.
Astrocytes sense neuromodulators to orchestrate neuronal activity and shape behavior
Astrocytes serve as crucial mediators of neuromodulatory processes previously attributed to direct communication between neurons, four new studies show.