Alzheimer’s disease
Recent articles
Alzheimer’s scientist forced to retract paper during his own replication effort
Gary Dunbar, a neuroscientist at Central Michigan University, was attempting to redo the 2020 paper after a collaborator admitted to using flawed data in the original work.

Alzheimer’s scientist forced to retract paper during his own replication effort
Gary Dunbar, a neuroscientist at Central Michigan University, was attempting to redo the 2020 paper after a collaborator admitted to using flawed data in the original work.
Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease
To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.

Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease
To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.
‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt
In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community’s “Grand Plan.”

‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt
In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community’s “Grand Plan.”
Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology
Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.

Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology
Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
‘Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s,’ an excerpt
In his new book, published today, investigative journalist Charles Piller tells the story of the scientific misconduct that shook Alzheimer’s disease research to its core, and the neuroscientist who helped to expose it.

‘Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s,’ an excerpt
In his new book, published today, investigative journalist Charles Piller tells the story of the scientific misconduct that shook Alzheimer’s disease research to its core, and the neuroscientist who helped to expose it.
Say what? The Transmitter’s top quotes of 2024
“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.

Say what? The Transmitter’s top quotes of 2024
“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.
Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.

Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.

Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.
Skeptics challenge claims of Alzheimer’s disease transmission via growth hormone
Some people who received cadaver-derived human growth hormone may not have Alzheimer’s as previously suggested, according to a new Perspective article.

Skeptics challenge claims of Alzheimer’s disease transmission via growth hormone
Some people who received cadaver-derived human growth hormone may not have Alzheimer’s as previously suggested, according to a new Perspective article.
Explore more from The Transmitter
Autism-linked copy number variants always boost autism likelihood
By contrast, varied doses of the same genes decrease or increase the odds of five other conditions, with distinct biological consequences, two new preprints show.

Autism-linked copy number variants always boost autism likelihood
By contrast, varied doses of the same genes decrease or increase the odds of five other conditions, with distinct biological consequences, two new preprints show.
Everything everywhere all at once: Decision-making signals engage entire brain
The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.

Everything everywhere all at once: Decision-making signals engage entire brain
The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.
Astrocyte networks span large swaths of brain
The networks are plastic, connect brain regions that aren’t connected by neurons and may enable long-distance communication between astrocytes, a new preprint shows.
Astrocyte networks span large swaths of brain
The networks are plastic, connect brain regions that aren’t connected by neurons and may enable long-distance communication between astrocytes, a new preprint shows.