Amyloid beta
Recent articles
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.

Early trajectory of Alzheimer’s tracked in single-cell brain atlases
Inflammation in glia and the loss of certain inhibitory cells may kick off a disease cascade decades before diagnosis.
Skeptics challenge claims of Alzheimer’s disease transmission via growth hormone
Some people who received cadaver-derived human growth hormone may not have Alzheimer’s as previously suggested, according to a new Perspective article.

Skeptics challenge claims of Alzheimer’s disease transmission via growth hormone
Some people who received cadaver-derived human growth hormone may not have Alzheimer’s as previously suggested, according to a new Perspective article.
Putting a bright idea to the test
A surprising wave of findings in mice suggests that light and sound flickering at 40 hertz clears the brain of Alzheimer’s-disease-linked plaques. Several companies are hoping to prove it works in people.

Putting a bright idea to the test
A surprising wave of findings in mice suggests that light and sound flickering at 40 hertz clears the brain of Alzheimer’s-disease-linked plaques. Several companies are hoping to prove it works in people.
Reviving ‘inside-out’ hypothesis of amyloid beta to explain Alzheimer’s mysteries
New research is resurfacing old ideas about where the protein forms the disease’s hallmark plaques.

Reviving ‘inside-out’ hypothesis of amyloid beta to explain Alzheimer’s mysteries
New research is resurfacing old ideas about where the protein forms the disease’s hallmark plaques.
How inbreeding almost tanked an up-and-coming model of Alzheimer’s disease
But new genetic analyses and behavioral assays have made the Chilean degu a viable model again, researchers say.

How inbreeding almost tanked an up-and-coming model of Alzheimer’s disease
But new genetic analyses and behavioral assays have made the Chilean degu a viable model again, researchers say.
Carol Jennings, whose family’s genetics informed amyloid cascade hypothesis, dies at 70
Her advocacy work aided the discovery of a rare inherited form of early-onset Alzheimer’s disease and helped connect affected people with researchers.

Carol Jennings, whose family’s genetics informed amyloid cascade hypothesis, dies at 70
Her advocacy work aided the discovery of a rare inherited form of early-onset Alzheimer’s disease and helped connect affected people with researchers.
Explore more from The Transmitter
‘A gut punch:’ How U.S. neuroscience trainees are grappling with diversity-based funding flux
Ten trainees spoke with The Transmitter about how the precarious state of U.S. federal funding is affecting their research and career plans.

‘A gut punch:’ How U.S. neuroscience trainees are grappling with diversity-based funding flux
Ten trainees spoke with The Transmitter about how the precarious state of U.S. federal funding is affecting their research and career plans.
‘Bioethics and Brains: A Disciplined and Principled Neuroethics,’ an excerpt
In their new book, published earlier this week, Giordano and Shook examine how ethics can guide neuroscience research and its real-world applications.

‘Bioethics and Brains: A Disciplined and Principled Neuroethics,’ an excerpt
In their new book, published earlier this week, Giordano and Shook examine how ethics can guide neuroscience research and its real-world applications.
AI tool estimates social ability by analyzing speech
The system’s code and training data—drawn from one of the largest databases of speech recordings from autistic people—are openly available.

AI tool estimates social ability by analyzing speech
The system’s code and training data—drawn from one of the largest databases of speech recordings from autistic people—are openly available.