CNTNAP2
Recent articles
Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.
Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.
On the periphery: Thinking ‘outside the brain’ offers new ideas about autism
Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.
On the periphery: Thinking ‘outside the brain’ offers new ideas about autism
Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Mouse models help sniff out olfactory differences in autism
A range of presentations at Neuroscience 2022 tie atypical social behavior to trouble discriminating between odors in the animals.
Mouse models help sniff out olfactory differences in autism
A range of presentations at Neuroscience 2022 tie atypical social behavior to trouble discriminating between odors in the animals.
Oxytocin alters brain activity to boost sociability in mice missing autism gene
Infusions of the hormone oxytocin may make mice that model autism more social by normalizing their brain activity patterns.
Oxytocin alters brain activity to boost sociability in mice missing autism gene
Infusions of the hormone oxytocin may make mice that model autism more social by normalizing their brain activity patterns.
Fish, frogs, flies and other fauna in scientific firsts
Over the past century, scientists have used a variety of animal models to advance their understanding of the developing brain and autism.
Fish, frogs, flies and other fauna in scientific firsts
Over the past century, scientists have used a variety of animal models to advance their understanding of the developing brain and autism.
What studying worms, flies and fish says about autism
Researchers are increasingly turning to simple animals to learn about autism biology and find leads for new drugs.
What studying worms, flies and fish says about autism
Researchers are increasingly turning to simple animals to learn about autism biology and find leads for new drugs.
GABA agonist rescues auditory hypersensitivity in rats missing autism-linked gene CNTNAP2
The investigational drug arbaclofen may right an imbalance between inhibitory and excitatory signaling in the animals’ brains.
GABA agonist rescues auditory hypersensitivity in rats missing autism-linked gene CNTNAP2
The investigational drug arbaclofen may right an imbalance between inhibitory and excitatory signaling in the animals’ brains.
Cerebellum alterations crop up in mice missing autism gene
Deleting the autism-linked gene CNTNAP2 from mice leads to distinct cellular and electrical changes in the cerebellum, according to two unpublished studies presented virtually today at the 2021 Society for Neuroscience Global Connectome.
Cerebellum alterations crop up in mice missing autism gene
Deleting the autism-linked gene CNTNAP2 from mice leads to distinct cellular and electrical changes in the cerebellum, according to two unpublished studies presented virtually today at the 2021 Society for Neuroscience Global Connectome.
‘MoSeq’ identifies drug-specific behaviors in autism mouse model
A tool that relies on video cameras and machine learning can identify mice that have mutations in a top autism gene by their behaviors. It also detects how a widely used autism drug affects their movements.
‘MoSeq’ identifies drug-specific behaviors in autism mouse model
A tool that relies on video cameras and machine learning can identify mice that have mutations in a top autism gene by their behaviors. It also detects how a widely used autism drug affects their movements.
Explore more from The Transmitter
Meet the Autism Data Science Initiative grantees
The awarded projects plan to study gene-and-environment interactions in people, stem cells and organoids, as well as predictors of positive life outcomes in autistic youth and adults.
Meet the Autism Data Science Initiative grantees
The awarded projects plan to study gene-and-environment interactions in people, stem cells and organoids, as well as predictors of positive life outcomes in autistic youth and adults.
Exclusive: The 23 studies the FDA based its expanded leucovorin label on
The studies include 46 people, mostly toddlers, who have cerebral folate deficiency due to variants in a folate transporter.
Exclusive: The 23 studies the FDA based its expanded leucovorin label on
The studies include 46 people, mostly toddlers, who have cerebral folate deficiency due to variants in a folate transporter.
Autism researchers ‘pleasantly surprised’ by list of NIH data project grantees, despite initial concerns
An atypical funding mechanism, truncated application timeline and opaque review process had generated concern over the quality of projects that would be selected for the Autism Data Science Initiative.
Autism researchers ‘pleasantly surprised’ by list of NIH data project grantees, despite initial concerns
An atypical funding mechanism, truncated application timeline and opaque review process had generated concern over the quality of projects that would be selected for the Autism Data Science Initiative.