Simon Prades
Illustrator
From this contributor
Knowledge graphs can help make sense of the flood of cell-type data
These tools, widely used in the technology industry, could provide a foundation for the study of brain circuits.
Knowledge graphs can help make sense of the flood of cell-type data
Where do cell states end and cell types begin?
High-throughput transcriptomics offers powerful new methods for defining different types of brain cells. But we need to think more explicitly about how we use these data to distinguish a cell’s permanent identity from its transient states.
Where do cell states end and cell types begin?
Building a brain: How does it generate its exquisite diversity of cells?
High-throughput technologies have revealed new insights into how the brain develops. But a truly comprehensive map of neurodevelopment requires further advances.
Building a brain: How does it generate its exquisite diversity of cells?
Change of heart and mind: Autism’s ties to cardiac defects
Children with congenital heart disease have an increased likelihood of autism. Why?
Change of heart and mind: Autism’s ties to cardiac defects
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The genome offers a recipe, not a blueprint, for the brain
During brain development, genes set the rules and turn the knobs; self-organization does much of the rest.
The genome offers a recipe, not a blueprint, for the brain
During brain development, genes set the rules and turn the knobs; self-organization does much of the rest.
Autism research involving monkeys contends with uphill battle
Macaques and marmosets recapitulate the condition’s core traits better than mice can, but funding uncertainty and challenges at primate centers in the United States could make this work difficult to continue.
Autism research involving monkeys contends with uphill battle
Macaques and marmosets recapitulate the condition’s core traits better than mice can, but funding uncertainty and challenges at primate centers in the United States could make this work difficult to continue.
When is self-organization a mechanism in brain development?
Retinal waves offer a powerful example of a self-organizing system that can build structure without external guidance. The field would do well to embrace such phenomena more broadly as a type of mechanistic explanation.
When is self-organization a mechanism in brain development?
Retinal waves offer a powerful example of a self-organizing system that can build structure without external guidance. The field would do well to embrace such phenomena more broadly as a type of mechanistic explanation.