Corpus callosum
Brain structures grow differently in boys, men with autism
Autistic boys and men show notable differences in brain development, according to magnetic resonance imaging scans taken over a 16-year period.
![brains of different sizes in colorful, radiant space with echoing shapes](https://www.thetransmitter.org/wp-content/uploads/2021/05/20210519-Volumetric-844.jpg)
Brain structures grow differently in boys, men with autism
Autistic boys and men show notable differences in brain development, according to magnetic resonance imaging scans taken over a 16-year period.
Loss of a top autism gene may alter neuron structure
Mutations in the autism-linked gene ASH1L change how neurons grow and develop.
![Neurons show structural changes, seen in black and white.](https://www.thetransmitter.org/wp-content/uploads/2021/01/EZH2-inhib-rescue-cell-neuron844-1.jpg)
Loss of a top autism gene may alter neuron structure
Mutations in the autism-linked gene ASH1L change how neurons grow and develop.
Brain structure changes in autism, explained
Autistic people have distinct patterns of brain development, which sometimes result in differences in brain structure. Here's what we know about those differences.
![four brain areas marked with flags: Cortex, amygdala, hippocampus, cerebellum](https://www.thetransmitter.org/wp-content/uploads/2020/10/20201015-BrainStructure844.jpg)
Brain structure changes in autism, explained
Autistic people have distinct patterns of brain development, which sometimes result in differences in brain structure. Here's what we know about those differences.
Study links gene to inherited form of autism
Mutations in both copies of a gene called ACTL6B lead to autism, epilepsy and intellectual disability.
![](https://www.thetransmitter.org/wp-content/uploads/2020/06/ACTL6Brevised-844.jpg)
Study links gene to inherited form of autism
Mutations in both copies of a gene called ACTL6B lead to autism, epilepsy and intellectual disability.
Structure of brain matter in young autistic children may show distinct patterns
The long fibers of neurons in the brains of young children with autism are structured differently from those of their neurotypical peers — and from those of older children with the condition.
![group of six brain images from children show white matter, anomalies shown in red areas](https://www.thetransmitter.org/wp-content/uploads/2020/01/20200123-DiffusionWeighted-844.jpg)
Structure of brain matter in young autistic children may show distinct patterns
The long fibers of neurons in the brains of young children with autism are structured differently from those of their neurotypical peers — and from those of older children with the condition.
In new device, brain organoids ‘talk’ to each other
A novel cell culture device enables researchers to grow bundles of nerve fibers from stem cells, mimicking the tissue that connects distant parts of the brain.
![Two organoids connected by nerve fibers](https://www.thetransmitter.org/wp-content/uploads/2019/06/20190614-MiniBrains844.jpg)
In new device, brain organoids ‘talk’ to each other
A novel cell culture device enables researchers to grow bundles of nerve fibers from stem cells, mimicking the tissue that connects distant parts of the brain.
‘Outmoded’ mouse models of autism may still yield new advances
Many researchers question the value of three early mouse models of autism, but the models have their staunch supporters.
![illustration of mouse on sale in a city](https://www.thetransmitter.org/wp-content/uploads/2018/03/Spectrum_SpecialReport_Mice_PasseModels_FINAL_REVISED.jpg)
‘Outmoded’ mouse models of autism may still yield new advances
Many researchers question the value of three early mouse models of autism, but the models have their staunch supporters.
Decoding the overlap between autism and ADHD
Autism and attention deficit hyperactivity disorder often coincide, but the search for common biological roots has turned up conflicting evidence.
Decoding the overlap between autism and ADHD
Autism and attention deficit hyperactivity disorder often coincide, but the search for common biological roots has turned up conflicting evidence.
Three autism mouse models marked by defects in same circuit
Problems with social interactions stem from faulty wiring of a single circuit spanning distant brain regions, results from three mouse models of autism suggest.
![mouse with a sensor connected to brain](https://www.thetransmitter.org/wp-content/uploads/2015/10/20151022SFNCircuitDefects-844.jpg)
Three autism mouse models marked by defects in same circuit
Problems with social interactions stem from faulty wiring of a single circuit spanning distant brain regions, results from three mouse models of autism suggest.
Off-key outcomes; visualizing variants; urine indifference and more
Music therapy proves ineffective for autism, brain structures differ with 16p11.2 duplications and deletions, and mice missing NLGN3 may influence the sociability of their littermates.
Off-key outcomes; visualizing variants; urine indifference and more
Music therapy proves ineffective for autism, brain structures differ with 16p11.2 duplications and deletions, and mice missing NLGN3 may influence the sociability of their littermates.
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New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.
![Research image of neurons in the fly’s ventral nerve cord.](https://www.thetransmitter.org/wp-content/uploads/2024/07/lede-motormodules-1200-1024x692.webp)
New connectomes fly beyond the brain
Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.
Building an autism research registry: Q&A with Tony Charman
A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.
![Illustration of researchers talking to laypeople amidst strands of DNA.](https://www.thetransmitter.org/wp-content/uploads/2024/07/1200_Charman-1024x687.webp)
Building an autism research registry: Q&A with Tony Charman
A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.
![](https://www.thetransmitter.org/wp-content/uploads/2024/07/paincircuit-1200-1024x692.webp)
Cerebellar circuit may convert expected pain relief into real thing
The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.