Dendrites

Recent articles

Detailed image of neurons in the mouse visual cortex.

Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain

A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

By Katie Moisse
9 April 2025 | 6 min listen
Raphael Yuste leaning on a bench in his lab. A red filter colors the scene.

Releasing the Hydra with Rafael Yuste

Losing HHMI Investigator status prompted Yuste to study neural networks in a new way.

By Brady Huggett, Shaena Montanari
4 April 2025 | 10 min read
Dendritic spine images.

Targeting NMDA receptor subunit reverses fragile X traits in mice

The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.

By Angie Voyles Askham
6 March 2025 | 5 min read
Research image of excitatory synapses in the prefrontal cortex.

Synaptic anomalies in autistic people support imbalance hypothesis

Increased excitatory and decreased inhibitory synapses in the prefrontal cortex of autistic people suggest broader impacts on brain function and connectivity.

By Giorgia Guglielmi
27 June 2024 | 4 min read
Neural progenitor cells in a culture medium, color-enhanced scanning electron micrograph (SEM).

Autism subgroups converge on cell growth pathway

Faulty mTOR signaling, implicated in syndromic forms of autism, also hinders cells grown from people with idiopathic autism or autism-linked deletions on chromosome 16.

By Angie Voyles Askham
2 April 2024 | 5 min listen

Neurons making memories shush their neighbors

When neurons strengthen their synapses, they “infect” surrounding cells with a virus-like protein to weaken those cells’ excitatory connections, according to a new preprint.

By Holly Barker
22 March 2024 | 5 min read
Research image of microglia in mice.

Microglial overreaction to atypical neurons may drive autism

In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.

By Holly Barker
21 March 2024 | 5 min read
A research image of neuronal dendrites in mice.

Top autism-linked genes join forces to shape synaptic plasticity

The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

By Holly Barker
29 January 2024 | 5 min read
Research image of mutations in mouse cortical neurons.

Mutations in multipurpose gene deal dendrites a double whammy

The mutations disrupt protein translation as well as the cell’s skeleton, according to a new study.

By Holly Barker
4 October 2023 | 5 min listen
Research image of neurons.

Abundant motor proteins disrupt cries in FOXP2 mice

Knocking down the gene that codes for the proteins normalizes the vocalizations.

By Laura Dattaro, Maaisha Osman
28 July 2023 | 3 min read

Explore more from The Transmitter

Illustration of overlapping, multi-colored human head silhouettes.

CDC autism prevalence numbers warrant attention—but not in the way RFK Jr. proposes

The head of the U.S. Department of Health and Human Services is ignoring decades of research findings.

By Lynn Waterhouse
1 May 2025 | 6 min read
A red speech bubble emanates from a megaphone.

‘These plans are simply not acceptable’: Q&A with Helen Tager-Flusberg

Last week, Tager-Flusberg formed the Coalition of Autism Scientists to push back on the U.S. government’s plans for autism research, as described by Health and Human Services Secretary RFK Jr. The coalition already has 220 members.

By Sydney Wyatt
1 May 2025 | 5 min read
Illustration of a lab coat being wiped away.

Federal funding cuts imperil next generation of autism researchers

As the International Society for Autism Research’s annual meeting begins, its next president reflects on a brewing crisis.

By Brian Boyd
30 April 2025 | 5 min read