Genetic testing

two people sit on opposite edges of a cliff

Spectrum 10K consultation report delayed

The U.K.-based genetics study launched the consultation more than a year ago in response to fierce criticism from autistic self-advocates.

By Cathleen O’Grady
7 March 2024 | 3 min read
Research image of neurons.

Abundant motor proteins disrupt cries in FOXP2 mice

Knocking down the gene that codes for the proteins normalizes the vocalizations.

By Laura Dattaro, Maaisha Osman
28 July 2023 | 3 min read
Illustration of half of a brain on the left and half of a heart on the right
Spectrum Microphone

Change of heart and mind: Autism’s ties to cardiac defects

Children with congenital heart disease have an increased likelihood of autism. Why?

By Lauren Schenkman
21 July 2023 | 12 min read
MRI scan of a 2-year-old child.

Mapping genetic influences on the infant brain: A chat with Rebecca Knickmeyer

Researchers know little about the ways genetic variants affect development in the infant brain. Knickmeyer, who launched the Organization for Imaging Genomics in Infancy, has spent the past five years trying to close the gap.

By Laura Dattaro
27 February 2023 | 6 min read
An illustration of doctors examining a larger-than-life DNA strand

Whole-genome trove ties new genes, variants to autism

A massive update to the MSSNG dataset gives qualified researchers ready access to explore autism’s genetic architecture on a cloud-based platform.

By Isabel Ruehl
12 December 2022 | 4 min read
Image displaying impeded interneuron development.
Spectrum Microphone

‘Assembloids’ lay bare autism-linked genes that hamper neuron development

The model enables the study of autism-linked genes at the earliest stages of neural development.

By Isabel Ruehl
30 November 2022 | 4 min read
Human silhouettes are seen against a colorful, abstract representation of a genetic sequence.

How geneticists can gain greater buy-in from the autistic community

My recommendations aim to foster a collaborative relationship between researchers and the Autistic community, resulting in an increase in the availability of genetic data.

By Wrigley Kline
9 September 2022 | 7 min read
Scientist examining DNA (deoxyribonucleic acid) results on a screen in a laboratory.
Spectrum Microphone

How an expert panel evaluates genes for autism genetic tests

About 15 percent of genes currently included in clinical genetic tests for autism or intellectual disability don’t have enough evidence to support their ties to the conditions, the panel found.

By Laura Dattaro
22 July 2022 | 8 min read
Genes Microphone

The most personalized medicine: Studying your own child’s rare condition

A handful of scientists are committed to advancing research on the autism-related genetic conditions their own children have.

By Lydia Denworth
7 July 2022 | 18 min listen

Prioritizing physical health in autism: Q&A with Alice Kuo

The principal investigator of the Autism Intervention Research Network on Physical Health wants to encourage more researchers to study physical health issues in autistic children and adults.

By Peter Hess
6 June 2022 | 4 min read

Explore more from The Transmitter

Illustration of a canyon landscape with an orange clock face in place of a sun.

How to teach this paper: ‘Behavioral time scale synaptic plasticity underlies CA1 place fields,’ by Bittner and Milstein et al. (2017)

Katie Bittner, Aaron Milstein and their colleagues found that cellular learning can happen over longer timescales than Hebb’s rule predicts. How long should we wait to teach students about this phenomenon?

By Ashley Juavinett
24 June 2024 | 11 min read
Portrait of Kaspar Podgorski standing in his lab wearing a helmet with a climbing rope over his shoulder.

Climbing to new heights: Q&A with Kaspar Podgorski

The optical physiologist tracks neural computations inside the lab and scales sheer rock faces outside—even after a life-changing fall.

By Elissa Welle
21 June 2024 | 8 min read
Research illustration groups genes by their effects on brain cell types.

Giant analysis reveals how autism-linked genes affect brain cell types

Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.

By Charles Q. Choi
20 June 2024 | 5 min read