Maternal infection

Recent articles

A pregnant woman seen in profile, sitting on the edge of a bed.

Maternal infection’s link to autism may be a mirage

Family-linked factors explain most associations between maternal illness and autism, a study of 1.1 million Danish children finds.

By Charles Q. Choi
6 March 2025 | 3 min read
Research image of microglia in mice.

Microglial overreaction to atypical neurons may drive autism

In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.

By Holly Barker
21 March 2024 | 5 min read
A research image of a mouse brain

Immune-activation model mice escape infantile amnesia, retain early memories

Male pups born to mothers treated with immune-stimulating molecules show autism-like behaviors and, unlike wildtype animals, do not lose memories formed during early life.

By Giorgia Guglielmi
11 January 2024 | 5 min read
A multiplexed image of human decidua.

Atlas charts cells of human placenta, uterus across early pregnancy

A new resource gives an unparalleled look at how fetal placental cells attach to the uterine wall and remodel maternal blood vessels to access nutrients.

By Emily Hayes
27 July 2023 | 4 min read
Research image of radial glial cells in a human brain organoid.

Immune molecule alters cellular makeup of human brain organoids

The changes may help explain the link between maternal infection and autism, though more research is needed.

By Charles Q. Choi
5 April 2023 | 5 min listen
Research image of the posterior insular cortex.

Maternal immune response dulls male rats’ social radar

Male rats prenatally exposed to a maternal immune response have atypical responses to other rats in distress, according to a new study.

By Angie Voyles Askham
27 March 2023 | 6 min listen
Illustration of a pregnant woman seated next to a large diagram of the brain featuring chromosomes, bacteria and other microbes.

The link between maternal infection and autism, explained

Having an infection during pregnancy is tied to a small increase in the chances of having an autistic child, but the connection may not be causal.

By Charles Q. Choi
13 December 2022 | 7 min read
Light micrograph of microglia cells stained with Rio Hortega’s silver carbonate method.

Autism’s sex bias tied to glial, immune cell gene expression

The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.

By Angie Voyles Askham
22 November 2022 | 3 min read
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: COVID-19 conclusions; diagnosis duplication; oxytocin again

This month’s newsletter explores the pandemic’s effects on autism rates, trends in co-occurring mental health conditions, and the impact of intranasal oxytocin.

By Emily Harris
10 November 2022 | 5 min read
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Medication timing; oxytocin amounts; sensory sameness

Parents’ health, treatment dosages and sensory perception feature in this month’s crop of null and replicated results.

By Emily Harris
13 October 2022 | 5 min read

Explore more from The Transmitter

Astrocytes sense neuromodulators to orchestrate neuronal activity and shape behavior

Astrocytes serve as crucial mediators of neuromodulatory processes previously attributed to direct communication between neurons, four new studies show.

By Claudia López Lloreda
27 June 2025 | 9 min listen

Authors correct image errors in Neuron paper that challenged microglia-to-neuron conversion

The issue with the supplementary figures likely does not change the conclusions of the paper, according to an outside expert.

By Shaena Montanari
26 June 2025 | 3 min read

Building a climate neuroscience subfield: Q&A with Angie Michaiel

Michaiel, a program officer at the Kavli Foundation, shares what it took to cultivate research on the relationship between climate change and the nervous system.

By Calli McMurray
26 June 2025 | 5 min read