Mouse models
Recent articles
Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.
Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.
Up and out with Peggy Mason
Mason helped define the rodent prosocial behavior field, but now she’s changing course.
Up and out with Peggy Mason
Mason helped define the rodent prosocial behavior field, but now she’s changing course.
This paper changed my life: Victoria Abraira on a tasty link between circuits and behavior
The findings from Charles Zuker’s lab put the taste system on the map, revealing that some fundamental principles of behavior are hardwired.
This paper changed my life: Victoria Abraira on a tasty link between circuits and behavior
The findings from Charles Zuker’s lab put the taste system on the map, revealing that some fundamental principles of behavior are hardwired.
Systems and circuit neuroscience need an evolutionary perspective
To identify fundamental neuroscientific principles that generalize across species, neuroscientists must frame their research through an evolutionary lens.
Systems and circuit neuroscience need an evolutionary perspective
To identify fundamental neuroscientific principles that generalize across species, neuroscientists must frame their research through an evolutionary lens.
The big idea with Diego Bohórquez
His theories around the neuropod have challenged the boundaries of classic ideas regarding gut-brain communication.
The big idea with Diego Bohórquez
His theories around the neuropod have challenged the boundaries of classic ideas regarding gut-brain communication.
Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind
Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.
Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind
Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.
‘Understudied secret’ in brain dampens nicotine drive in mice
The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.
‘Understudied secret’ in brain dampens nicotine drive in mice
The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.
Escaping groupthink: What animals’ behavioral quirks reveal about the brain
Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.
Escaping groupthink: What animals’ behavioral quirks reveal about the brain
Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.
Immune cells block pain in female mice only
Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.
Immune cells block pain in female mice only
Regulatory T cells in the spinal meninges release endogenous opioids in a sex-specific manner, new work shows.
Too much or too little brain synchrony may underlie autism subtypes
Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.
Too much or too little brain synchrony may underlie autism subtypes
Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.
Explore more from The Transmitter
NIH awarded 37 percent fewer neuroscience-related grants in 2025 than in past years
But the agency has spent nearly its entire budget for this fiscal year, which ends tomorrow.
NIH awarded 37 percent fewer neuroscience-related grants in 2025 than in past years
But the agency has spent nearly its entire budget for this fiscal year, which ends tomorrow.
Reproducibility is a team sport: Lessons from a large-scale collaboration
Building reproducible systems across labs is possible, even in large-scale neuroscience projects. You just need rigor, collaboration and the willingness to look your own practices dead in the eye.
Reproducibility is a team sport: Lessons from a large-scale collaboration
Building reproducible systems across labs is possible, even in large-scale neuroscience projects. You just need rigor, collaboration and the willingness to look your own practices dead in the eye.
Authors retract Science paper on controversial fMRI method
Several known but usually negligible MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted earlier this month.
Authors retract Science paper on controversial fMRI method
Several known but usually negligible MRI artifacts contribute to the neuronal activity signal picked up by the method, according to a preprint the authors posted earlier this month.