Pupillometry

Recent articles

Annimation of eye tracking application following the pupil in a man's eye.

Web app tracks pupil size in people, mice

The app relies on artificial intelligence and could help researchers standardize studies of pupil differences in autistic people and in mouse models of autism.

By Rahul Rao
8 October 2021 | 3 min read

Mice reveal roots of sensory issues tied to top autism gene

Mice with mutations in the autism-linked gene SYNGAP1 have trouble sensing touch, which may stem in part from brain-circuit alterations and dulled alertness.

By Peter Hess
23 November 2020 | 4 min read
Man working from home office.

INSAR 2020, from home

Like so many other events this year, autism’s biggest annual conference — the International Society for Autism Research meeting — was forced to go virtual because of the coronavirus pandemic.

By Spectrum
31 July 2020 | 15 min read
Close up view of human eye.
Spectrum Microphone

Autistic people may have trouble tuning out distractions

Pupil response suggests autistic people have atypical activity in a part of the brain that regulates attention.

By Laura Dattaro
4 May 2020 | 5 min read

Pupillary reflex in infancy may yield clues to autism

The pupils of babies later diagnosed with autism shrink more in response to light than those of their typical peers.

By Nicholette Zeliadt
25 June 2018 | 4 min read

Autism unsurprised; diagnostic camouflage; Neanderthal legacy and more

People with autism aren’t easily surprised, the social camouflage some girls and women with autism use may preclude diagnosis, and autism-related genes are rooted deep in human ancestry.

By Emily Willingham
4 August 2017 | 4 min read

Delayed pupil response to light may be early sign of autism

The pupils of preschoolers with autism are slow to constrict in response to light, a phenomenon that may serve as an early marker of autism risk.

By Nicholette Zeliadt
24 February 2017 | 4 min read

Shrinking pupils may mirror autism risk in babies

The pupils of 10-month-old infants who have a sibling with autism constrict unusually fast in response to flashes of light, hinting that this reflex could be an early sign of the disorder.

By Nicholette Zeliadt
20 March 2015 | 2 min read
A close-up photograph of an infant’s right ear.

Controversial study uncovers hearing glitch in autism

An ear muscle is more sensitive to loud sounds in children with autism than in controls, according to a study published 3 July in Autism Research. The researchers say this measure could serve as a clinical biomarker of the disorder, but others fiercely disagree.

By Virginia Hughes
29 July 2013 | 6 min read

Study links pupillary reflex, heart rate in autism

More than half of children with autism have a delayed pupillary response to light, along with a high heart rate and other physiological features, according an unpublished study presented Thursday at the 2013 International Meeting for Autism Research in San Sebastián, Spain.

By Laura Geggel
4 May 2013 | 3 min read

Explore more from The Transmitter

Illustration of children looking at a gigantic set of building blocks, some of which display genetic sequences on their surfaces.

Autism is more heritable in boys than in girls

If boys have greater inherited liability for autism, the female protective effect may not fully explain the sex difference in prevalence.

Illustration of a brain.

This paper changed my life – ‘Response of hippocampal synapses to natural stimulation patterns,’ by Dobrunz and Stevens

The work demonstrated how to effectively combine controlled in-vitro experiments and the messiness of natural brain patterns.

By Robert Froemke
17 September 2024 | 4 min read
Research image of microglia.

CDKL5 gene; cerebrospinal fluid; drug combo for fragile X syndrome

Here is a roundup of autism-related news and research spotted around the web for the week of 16 September.

By Jill Adams
17 September 2024 | 2 min read