SFN 2015

Neuron tag may shield synapses from brain’s pruning shears

A protective molecular tag on neurons can prevent microglia, the brain’s immune cells, from trimming away their connections with other neurons.

By Nicholette Zeliadt
12 November 2018 | 4 min read
mouse with a sensor connected to brain

Three autism mouse models marked by defects in same circuit

Problems with social interactions stem from faulty wiring of a single circuit spanning distant brain regions, results from three mouse models of autism suggest.

By Nicholette Zeliadt
8 November 2017 | 4 min read

Network analysis gives clues to other ailments in autism

Genes linked to autism are associated with a variety of other ailments, including cancer, heart conditions, autoimmune disorders and gut problems.

By Nicholette Zeliadt
25 October 2016 | 3 min read

Maternal immune molecule triggers autism symptoms in male mice

Rare antibodies taken from the blood of women who have a child with autism cause brain structure changes and autism-like symptoms in male mice.

By Nicholette Zeliadt
7 November 2015 | 4 min read

Over-synched brains trigger out-of-step social behavior

People with autism show excessively synchronized activity between brain regions while conversing with others.

By Sarah DeWeerdt
22 October 2015 | 4 min read

Male mice more vulnerable to tilt of gut-brain axis

Early disruption of the microbes that inhabit the gut can alter a mouse’s sociability long term.

By Sarah DeWeerdt
22 October 2015 | 4 min read

For autism mouse models, gender matters

The mutation that leads to Angelman syndrome may affect the brains of female mice more severely than those of male mice.

By Jessica Wright
22 October 2015 | 3 min read

Autism model reveals brain processes behind ‘super’ skills

Structural changes in the connections between neurons may underlie the enhanced learning and motor skills of a mouse model of autism.

By Nicholette Zeliadt
21 October 2015 | 4 min read

One form of immune gene tracks with autism traits

A variant in a gene that regulates immune responses is more common in children with autism than in those without this disorder.

By Katie Moisse
21 October 2015 | 2 min read

Prairie vole study digs up link between Prozac, oxytocin

Prairie vole pups exposed to the antidepressant fluoxetine in the womb show autism-like behaviors and lose some receptors for oxytocin and vasopressin.

By Rachel Zamzow
21 October 2015 | 3 min read

Explore more from The Transmitter

Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read
Illustration of researchers talking to laypeople amidst strands of DNA.

Building an autism research registry: Q&A with Tony Charman

A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.

By Cathleen O’Grady
25 July 2024 | 8 min read

Cerebellar circuit may convert expected pain relief into real thing

The newly identified circuit taps into the brain’s opioid system to provide a top-down form of pain relief.

By Angie Voyles Askham
24 July 2024 | 6 min read