Almost every human cell teems with a potpourri of tiny powerhouses: mitochondria. Up to thousands of them. These organelles use oxygen to convert the nutrients from the food you eat into a form of energy the body can use. The brain consumes a lot of this energy — about 20 percent. Could changes in mitochondria, then, affect how the brain functions and contribute to autism? Read the related article, Meet the ‘mitomaniacs’ who say mitochondria matter in autism.
Mitochondria: An energy explanation for autism
People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.
By
Laura Dattaro
22 November 2021 | 3 min watch
Illustration by Mengxin Li
Recommended reading

Boosting SCN2A expression reduces seizures in mice
By
Charles Q. Choi
9 October 2025 | 5 min read

Meet the Autism Data Science Initiative grantees
By
Calli McMurray
3 October 2025 | 2 min read
Explore more from The Transmitter

New questions around motor neurons and plasticity
By
David Adam
10 October 2025 | 11 min listen
Nikolay Kukushkin discusses his book, ‘One Hand Clapping: Unraveling the Mystery of the Human Mind’
By
Paul Middlebrooks
8 October 2025 | 1 min read

One year of FlyWire: How the resource is redefining Drosophila research
By
Francisco J. Rivera Rosario
7 October 2025 | 19 min listen
Cite this article: