Stem cells
Recent articles
Lipids enter brain mapping limelight
Two new studies, including the first whole-brain lipid atlas in mice, uncover unforeseen complexity and influence during pregnancy and aging.
Lipids enter brain mapping limelight
Two new studies, including the first whole-brain lipid atlas in mice, uncover unforeseen complexity and influence during pregnancy and aging.
Human brain organoids come of age—but still have room to grow
The U.S. government has touted organoids as an alternative to animals for studying the brain. The model has improved since its debut in 2013, but scientists are still working to overcome key limitations: immaturity, consistency and the lack of vascularization.
Human brain organoids come of age—but still have room to grow
The U.S. government has touted organoids as an alternative to animals for studying the brain. The model has improved since its debut in 2013, but scientists are still working to overcome key limitations: immaturity, consistency and the lack of vascularization.
Hasty stem cells highlight potential limitation with cortical organoids
The models recapitulate many key developmental processes, but some radial glial cells in mouse organoids make neurons earlier than they should.
Hasty stem cells highlight potential limitation with cortical organoids
The models recapitulate many key developmental processes, but some radial glial cells in mouse organoids make neurons earlier than they should.
Diverse autism genes derail common developmental pathways
Multiple genetic mouse models initially show delayed cortical development, but the animals’ molecular trajectories diverge within weeks after birth, a new study finds.
Diverse autism genes derail common developmental pathways
Multiple genetic mouse models initially show delayed cortical development, but the animals’ molecular trajectories diverge within weeks after birth, a new study finds.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
New organoid atlas unveils four neurodevelopmental signatures
The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.
New organoid atlas unveils four neurodevelopmental signatures
The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.
Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”
Microglia nurture young interneurons
The immune cells secrete a growth factor that “sets the supply of GABAergic interneurons in the developing brain.”
Why hype for autism stem cell therapies continues despite dead ends
After numerous tests, there is still no evidence that these experimental treatments help, so now is not the time to expand access to them.
Why hype for autism stem cell therapies continues despite dead ends
After numerous tests, there is still no evidence that these experimental treatments help, so now is not the time to expand access to them.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Explore more from The Transmitter
‘Brain Flows: How Network Dynamics Compose the Human Mind,’ an excerpt
In his new book, published today, Michael W. Cole examines how the movement of neuronal activity between neuronal populations shapes free will, intelligence and creativity. In this excerpt from Chapter 1, Cole explores why activity flows could unify efforts to map brain functions and connectivity.
‘Brain Flows: How Network Dynamics Compose the Human Mind,’ an excerpt
In his new book, published today, Michael W. Cole examines how the movement of neuronal activity between neuronal populations shapes free will, intelligence and creativity. In this excerpt from Chapter 1, Cole explores why activity flows could unify efforts to map brain functions and connectivity.
Prenatal pruning of neurons with copy number variants; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 2 November.
Prenatal pruning of neurons with copy number variants; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 2 November.
New Stanford initiative aims to build digital twin of human brain
The effort, funded by private donors, seeks to train the model on a trove of MRI and magnetoencephalography data that scientists plan to collect over the next five years—but questions about its scientific utility and feasibility remain.
New Stanford initiative aims to build digital twin of human brain
The effort, funded by private donors, seeks to train the model on a trove of MRI and magnetoencephalography data that scientists plan to collect over the next five years—but questions about its scientific utility and feasibility remain.