Drosophila

Recent articles

Research image of connectomes for two fly species.

Cross-species connectome comparison shows uneven olfactory circuit evolution in flies

The findings start to reveal evolutionary changes that may have helped two species develop different olfactory preferences and adapt to their particular environments.

By Marta Hill
1 August 2025 | 6 min read
Different colored rectangles form the shapes of a bird, fish and insect.

Systems and circuit neuroscience need an evolutionary perspective

To identify fundamental neuroscientific principles that generalize across species, neuroscientists must frame their research through an evolutionary lens.

By Karl Farrow, Katja Reinhard
16 July 2025 | 7 min listen
Illustration of a fly in various poses.

This paper changed my life: Bradley Dickerson on how a 1940s fly neuroanatomy paper influences his research to this day

This classic paper by zoologist John Pringle describes the haltere—a small structure in flies that plays a crucial role in flight control. It taught me to think about circuits and behavior as greater than the sum of their parts.

By Bradley Dickerson
17 June 2025 | 5 min listen
Research image of developing axons in the fly brain.

How developing neurons simplify their search for a synaptic mate

Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

By Calli McMurray
6 June 2025 | 7 min listen
A crumpled sheet of paper with a fly printed on it.

FlyBase funding squashed amid Harvard grant terminations

The team behind the Drosophila genetics database is now requesting donations from labs to keep the resource afloat.

By Calli McMurray
4 June 2025 | 4 min read
Research image of connectivity in the fly brain.

Connectomics 2.0: Simulating the brain

With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.

By Laura Dattaro
2 May 2025 | 11 min read
Multiple people look together at a whiteboard in a lab.

Why practical summer courses in neuroscience matter

Among other reasons, this tradition helps researchers rekindle the unfettered joy that initially brought them to the field.

By John Tuthill
13 January 2025 | 7 min read
Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read
A dense reconstruction of layer 2/3 neurons of the mouse visual cortex containing 394 neurons and 3.2 million synapses.

To develop better nervous-system visualizations, we need to think BIG

With a full mouse connectome on the horizon, neuroscience needs to overcome its legacy of minimalism and embrace the contemporary challenge of representing whole-nervous-system connectivity.

By Tyler Sloan
8 July 2024 | 8 min read
Close-up image of a dead fly with visible growths protruding from its abdomen due to Entomophthora fungus infection.

Mind control in zombie flies: Q&A with Carolyn Elya

A parasitic fungus compels its insect host to behave in strange ways by hijacking secretory neurons and circadian pathways.

By Shaena Montanari
25 June 2024 | 5 min read

Explore more from The Transmitter

Chris Rozell explains how brain stimulation and AI are helping to treat mental disorders

Rozell and his colleagues, using deep brain stimulation and explainable artificial intelligence, have developed tools to help people with treatment-resistant depression.

By Paul Middlebrooks
13 August 2025 | 1 min read
Illustration of a musical staff with notes represented by neurons.

This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations

By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.

By Abigail Person
12 August 2025 | 6 min listen
Research image of mouse auditory brainstems.

Prosocial effects of oxytocin are state dependent; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 11 August.

By Jill Adams
12 August 2025 | 2 min read