Epilepsy
Recent articles
Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.

Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.
Expediting clinical trials for profound autism: Q&A with Matthew State
Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.

Expediting clinical trials for profound autism: Q&A with Matthew State
Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.
Split gene therapy delivers promise in mice modeling Dravet syndrome
The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.

Split gene therapy delivers promise in mice modeling Dravet syndrome
The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.
Organoids and assembloids offer a new window into human brain
These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.

Organoids and assembloids offer a new window into human brain
These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.
New catalog charts familial ties from autism to 90 other conditions
The research tool reveals associations stretching across three generations.

New catalog charts familial ties from autism to 90 other conditions
The research tool reveals associations stretching across three generations.
As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.
Tail of hippocampus may be hub for seizures in mice and people
This little-studied subregion, called the fasciola cinereum, could be a new surgical target for people with treatment-resistant epilepsy.

Tail of hippocampus may be hub for seizures in mice and people
This little-studied subregion, called the fasciola cinereum, could be a new surgical target for people with treatment-resistant epilepsy.
On a bold mission to re-engineer brain parts
A European consortium is on a quest to restore typical brain activity in people with epilepsy, using a mash-up of custom organoids, microelectronics and artificial intelligence.

On a bold mission to re-engineer brain parts
A European consortium is on a quest to restore typical brain activity in people with epilepsy, using a mash-up of custom organoids, microelectronics and artificial intelligence.
Into the woods with Susan Masino
When she isn't researching the links between metabolism and brain activity, this neuroscientist logs time in forests and advocates for protecting green spaces.

Into the woods with Susan Masino
When she isn't researching the links between metabolism and brain activity, this neuroscientist logs time in forests and advocates for protecting green spaces.
Cortical interneurons derive differently in human brains
Excitatory neurons and some inhibitory neurons in the adult human cortex share parents, challenging the longstanding idea that the two cell types have different origins.

Cortical interneurons derive differently in human brains
Excitatory neurons and some inhibitory neurons in the adult human cortex share parents, challenging the longstanding idea that the two cell types have different origins.
Explore more from The Transmitter
Oxytocin shapes both mouse mom and pup behavior
Distressed pups emit distinct cries for help, which depend on oxytocin neurons in their hypothalamus.

Oxytocin shapes both mouse mom and pup behavior
Distressed pups emit distinct cries for help, which depend on oxytocin neurons in their hypothalamus.
Michael Breakspear and Mac Shine explain how brain processing changes across neural population scales
Breakspear and Shine find a scale-free property of brain activity that is conserved across diverse species, suggesting that a universal principle of brain activity underlies cognition.
Michael Breakspear and Mac Shine explain how brain processing changes across neural population scales
Breakspear and Shine find a scale-free property of brain activity that is conserved across diverse species, suggesting that a universal principle of brain activity underlies cognition.
Protein interactions important to SYNGAP1-related conditions; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 8 September.

Protein interactions important to SYNGAP1-related conditions; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 8 September.