Metabolism

Recent articles

Collage of digestive-system organs, the brain and various shapes and figures.

Going against the gut: Q&A with Kevin Mitchell on the autism-microbiome theory

A new review of 15 years of studies on the connection between the microbiome and autism reveals widespread statistical and conceptual errors.

By Lauren Schenkman
13 November 2025 | 7 min read
Pixelated human brain scans showing the distribution of mitochondria.

Mitochondrial ‘landscape’ shifts across human brain

Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.

By Claudia López Lloreda
25 April 2025 | 6 min read
Research image of brain glucose levels in mice.

Food for thought: Neuronal fuel source more flexible than previously recognized

The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.

By Giorgia Guglielmi
7 February 2025 | 6 min read

Into the woods with Susan Masino

When she isn't researching the links between metabolism and brain activity, this neuroscientist logs time in forests and advocates for protecting green spaces.

By Emmet Fraizer
5 January 2024 | 5 min read
Research image of the blood-brain barrier.

Rare autism-linked mutation starves growing neurons of essential nutrients

The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.

By Lauren Schenkman
10 April 2023 | 5 min read
A photograph of an infant's foot.

Dietary changes ease traits in rare autism-linked condition

Early treatment with nutritional supplements and a high-protein diet forestalls some neurodevelopmental problems for children with BCKDK deficiency.

By Lauren Schenkman
21 February 2023 | 5 min read
An adult administers a medication to an infant.

Experimental drug shows promise for autism-linked syndromes

The drug quells seizures in children with Dravet syndrome or Lennox-Gastaut syndrome.

By Charles Q. Choi
2 September 2022 | 5 min read
Brain made up of two different medicines

Meet the company trying precision medicine for autism

Swiss biotech Stalicla hopes to bring precision medicine to autism. Experts praise efforts to identify autism subgroups, but evidence to support the company’s claims has yet to be seen.

By Giorgia Guglielmi
27 June 2022 | 10 min read

Altering metabolic pathway spurs neuronal, behavioral changes in mice

Overexpressing genes involved in the pathway, which regulates protein quality, changes repetitive behaviors in the animals.

By Laura Dattaro
5 April 2022 | 5 min read

Mitochondria: An energy explanation for autism

People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.

By Laura Dattaro
22 November 2021 | 3 min watch

Explore more from The Transmitter

Research images of the mouse visual cortex.

Astrocytes stabilize circuits in adult mouse brain

The glial cells secrete a protein that suppresses plasticity post-development.

By Holly Barker
6 January 2026 | 5 min read
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Profiles of neurodevelopmental conditions; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 5 January.

By Jill Adams
6 January 2026 | 1 min read
Brain-shaped go-karts race.

The 1,000 neuron challenge

A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.

By Tom Stafford
5 January 2026 | 7 min read

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