Metabolism
Recent articles
Mitochondrial ‘landscape’ shifts across human brain
Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.

Mitochondrial ‘landscape’ shifts across human brain
Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.
Food for thought: Neuronal fuel source more flexible than previously recognized
The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.

Food for thought: Neuronal fuel source more flexible than previously recognized
The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.
Into the woods with Susan Masino
When she isn't researching the links between metabolism and brain activity, this neuroscientist logs time in forests and advocates for protecting green spaces.

Into the woods with Susan Masino
When she isn't researching the links between metabolism and brain activity, this neuroscientist logs time in forests and advocates for protecting green spaces.
Rare autism-linked mutation starves growing neurons of essential nutrients
The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.

Rare autism-linked mutation starves growing neurons of essential nutrients
The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.
Dietary changes ease traits in rare autism-linked condition
Early treatment with nutritional supplements and a high-protein diet forestalls some neurodevelopmental problems for children with BCKDK deficiency.

Dietary changes ease traits in rare autism-linked condition
Early treatment with nutritional supplements and a high-protein diet forestalls some neurodevelopmental problems for children with BCKDK deficiency.
Experimental drug shows promise for autism-linked syndromes
The drug quells seizures in children with Dravet syndrome or Lennox-Gastaut syndrome.

Experimental drug shows promise for autism-linked syndromes
The drug quells seizures in children with Dravet syndrome or Lennox-Gastaut syndrome.
Meet the company trying precision medicine for autism
Swiss biotech Stalicla hopes to bring precision medicine to autism. Experts praise efforts to identify autism subgroups, but evidence to support the company’s claims has yet to be seen.

Meet the company trying precision medicine for autism
Swiss biotech Stalicla hopes to bring precision medicine to autism. Experts praise efforts to identify autism subgroups, but evidence to support the company’s claims has yet to be seen.
Altering metabolic pathway spurs neuronal, behavioral changes in mice
Overexpressing genes involved in the pathway, which regulates protein quality, changes repetitive behaviors in the animals.

Altering metabolic pathway spurs neuronal, behavioral changes in mice
Overexpressing genes involved in the pathway, which regulates protein quality, changes repetitive behaviors in the animals.
Mitochondria: An energy explanation for autism
People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.
Mitochondria: An energy explanation for autism
People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.
Meet the ‘mitomaniacs’ who say mitochondria matter in autism
Clues that problems with mitochondria contribute to autism have been accumulating for decades. In the past five years, a mutant mouse and a flurry of findings have energized the field.

Meet the ‘mitomaniacs’ who say mitochondria matter in autism
Clues that problems with mitochondria contribute to autism have been accumulating for decades. In the past five years, a mutant mouse and a flurry of findings have energized the field.
Explore more from The Transmitter
Nature retracts paper on novel brain cell type against authors’ wishes
A 2022 paper was retracted after an independent team of researchers reanalyzed the data and questioned its validity.

Nature retracts paper on novel brain cell type against authors’ wishes
A 2022 paper was retracted after an independent team of researchers reanalyzed the data and questioned its validity.
Rise in autism prevalence but not traits; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 7 July.

Rise in autism prevalence but not traits; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 7 July.
Drosophila, like vertebrates, filter sensory information during sleep
Predictive sensory processing in sleeping Drosophila echoes vertebrate research, establishing an evolutionarily conserved neural signature of sleep.

Drosophila, like vertebrates, filter sensory information during sleep
Predictive sensory processing in sleeping Drosophila echoes vertebrate research, establishing an evolutionarily conserved neural signature of sleep.