ANK2
Recent articles
Top autism-linked genes join forces to shape synaptic plasticity
The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

Top autism-linked genes join forces to shape synaptic plasticity
The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.
Fishing for protein partners nets clues to autism
Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway.

Fishing for protein partners nets clues to autism
Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway.
Dispatches from SfN 2021: Mitochondria, Rett therapy and oxytocin
These short reports from Spectrum journalists highlight some of the autism-related findings that caught our attention at the meeting this past week.

Dispatches from SfN 2021: Mitochondria, Rett therapy and oxytocin
These short reports from Spectrum journalists highlight some of the autism-related findings that caught our attention at the meeting this past week.
‘Neurons on a chip’ reveal patterns across autism-linked conditions
Activity patterns of neuronal networks link different genetic subtypes of autism that have similar traits, according to new unpublished research.

‘Neurons on a chip’ reveal patterns across autism-linked conditions
Activity patterns of neuronal networks link different genetic subtypes of autism that have similar traits, according to new unpublished research.
Mutations in frogs point to autism genes’ shared role in neurogenesis
Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.

Mutations in frogs point to autism genes’ shared role in neurogenesis
Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.
Cell maps reveal diversity of neurons in gut
An atlas that details gene expression in neurons and other cells from the intestines of mice and people may help to elucidate the link between gut problems and autism.

Cell maps reveal diversity of neurons in gut
An atlas that details gene expression in neurons and other cells from the intestines of mice and people may help to elucidate the link between gut problems and autism.
Mice reveal how top autism gene may disrupt brain structure
Mutations in an autism gene called ANK2 may alter brain wiring by causing the growth of excess neuronal connections.

Mice reveal how top autism gene may disrupt brain structure
Mutations in an autism gene called ANK2 may alter brain wiring by causing the growth of excess neuronal connections.
Some ‘autism genes’ show stronger ties to related conditions
The largest autism sequencing study to date implicates 99 genes in the condition — but nearly half have a tighter link to intellectual disability or developmental delay.

Some ‘autism genes’ show stronger ties to related conditions
The largest autism sequencing study to date implicates 99 genes in the condition — but nearly half have a tighter link to intellectual disability or developmental delay.
‘Retired’ mice find new life as top models for autism
As the list of autism candidate genes grows, some mouse models of the genes turn up in long-forgotten studies.

‘Retired’ mice find new life as top models for autism
As the list of autism candidate genes grows, some mouse models of the genes turn up in long-forgotten studies.
Brain’s bridge could yield clues to faulty wiring in autism
Decoding distortions in the brain’s largest nerve tract could lay bare basic problems with long-range neural connections in autism.
Brain’s bridge could yield clues to faulty wiring in autism
Decoding distortions in the brain’s largest nerve tract could lay bare basic problems with long-range neural connections in autism.
Explore more from The Transmitter
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.

Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
What infant fMRI is revealing about the developing mind
Cognitive neuroscientists have finally clocked how to perform task-based functional MRI experiments in awake babies—long known for their inability to lie still or take direction. Next, they aim to watch cognition take shape and settle a debate about our earliest memories—with one group publishing a big clue today.

What infant fMRI is revealing about the developing mind
Cognitive neuroscientists have finally clocked how to perform task-based functional MRI experiments in awake babies—long known for their inability to lie still or take direction. Next, they aim to watch cognition take shape and settle a debate about our earliest memories—with one group publishing a big clue today.
Molecular changes after MECP2 loss may drive Rett syndrome traits
Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.

Molecular changes after MECP2 loss may drive Rett syndrome traits
Knocking out the gene in adult mice triggered up- and down-regulated expression of myriad genes weeks before there were changes in neuronal function.