ANK2
Top autism-linked genes join forces to shape synaptic plasticity
The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.
Top autism-linked genes join forces to shape synaptic plasticity
Fishing for protein partners nets clues to autism
Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway.
Fishing for protein partners nets clues to autism
Dispatches from SfN 2021: Mitochondria, Rett therapy and oxytocin
These short reports from Spectrum journalists highlight some of the autism-related findings that caught our attention at the meeting this past week.
Dispatches from SfN 2021: Mitochondria, Rett therapy and oxytocin
‘Neurons on a chip’ reveal patterns across autism-linked conditions
Activity patterns of neuronal networks link different genetic subtypes of autism that have similar traits, according to new unpublished research.
‘Neurons on a chip’ reveal patterns across autism-linked conditions
Mutations in frogs point to autism genes’ shared role in neurogenesis
Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.
Mutations in frogs point to autism genes’ shared role in neurogenesis
Cell maps reveal diversity of neurons in gut
An atlas that details gene expression in neurons and other cells from the intestines of mice and people may help to elucidate the link between gut problems and autism.
Cell maps reveal diversity of neurons in gut
Mice reveal how top autism gene may disrupt brain structure
Mutations in an autism gene called ANK2 may alter brain wiring by causing the growth of excess neuronal connections.
Mice reveal how top autism gene may disrupt brain structure
Some ‘autism genes’ show stronger ties to related conditions
The largest autism sequencing study to date implicates 99 genes in the condition — but nearly half have a tighter link to intellectual disability or developmental delay.
Some ‘autism genes’ show stronger ties to related conditions
‘Retired’ mice find new life as top models for autism
As the list of autism candidate genes grows, some mouse models of the genes turn up in long-forgotten studies.
‘Retired’ mice find new life as top models for autism
Brain’s bridge could yield clues to faulty wiring in autism
Decoding distortions in the brain’s largest nerve tract could lay bare basic problems with long-range neural connections in autism.
Brain’s bridge could yield clues to faulty wiring in autism
Explore more from The Transmitter
How inbreeding almost tanked an up-and-coming model of Alzheimer’s disease
But new genetic analyses and behavioral assays have made the Chilean degu a viable model again, researchers say.
How inbreeding almost tanked an up-and-coming model of Alzheimer’s disease
But new genetic analyses and behavioral assays have made the Chilean degu a viable model again, researchers say.
Sex-dependent cytokine release; KATNAL2 gene; auditory processing in fragile X syndrome
Here is a roundup of autism-related news and research spotted around the web for the week of 20 May.
Sex-dependent cytokine release; KATNAL2 gene; auditory processing in fragile X syndrome
Here is a roundup of autism-related news and research spotted around the web for the week of 20 May.
At the credit crossroads: Modern neuroscience needs a cultural shift to adopt new authorship practices
Old heuristics to acknowledge contributors—calling out first and last authors, with everyone else in between—don’t work well for large collaborative and interdisciplinary projects, yet they remain the default.
At the credit crossroads: Modern neuroscience needs a cultural shift to adopt new authorship practices
Old heuristics to acknowledge contributors—calling out first and last authors, with everyone else in between—don’t work well for large collaborative and interdisciplinary projects, yet they remain the default.