Cancer

A research image of X chromosomes with Fragile X syndrome

Understanding fragile X syndrome

Just in time for Fragile X Awareness Month, The Transmitter rounds up notable coverage.

By Daisy Yuhas
4 July 2024 | 2 min read
Image of a series of red sticky notes protruding from a stack of white paper.

Faked results lead to retraction of high-profile cancer neuroscience study

An investigation found that the experiments required more animals than the scientists had purchased.

By Dalmeet Singh Chawla
18 June 2024 | 4 min read
Photograph of a gloved hand pointing to a computer screen that is displaying an image of a mouse brain.

Going deep: The Transmitter’s top long-form stories in 2023

Our favorite features and book excerpts from the past year delved into the neurobiology of cancer; problems with survey data; free will; mathematical minds; and questions around one startup’s quest to treat brain conditions with cell therapies.

By The Transmitter
26 December 2023 | 4 min read
Close-up of a green glass slide embedded with dozens of tiny electrodes.
Neurobiology Microphone

Making cancer nervous

Nerve cells in the brain and throughout the body can turbocharge tumor growth — a finding that not only expands conventional ideas about the nervous system but points to novel therapeutic targets for a range of malignancies.

By Sarah DeWeerdt
13 November 2023 | 24 min listen
Illustration of mitochondria as a kind of Stonehenge, with the shapes standing upright, casting shadows, against a blue sky.
Spectrum Microphone

Mitochondria mediate effects of PTEN mutations

Whole-genome sequencing data — which include information about mitochondrial DNA — offer clues to why mutations in the same gene can lead to autism or cancer.

By Katie Moisse
26 June 2023 | 4 min read
Illustration of a binocular microscope with an X Chromosome in one eyepiece and cancer cells in the other.
Spectrum Microphone

The cloudy connection between fragile X and cancer

People with the autism-linked syndrome lack a protein implicated in several cancers, but it’s unclear whether — or how — they are protected from malignancies.

By Giorgia Guglielmi
28 September 2022 | 8 min read
Micrographs comparing mouse striatal neurons missing TSHZ3 and wildtype striatal neurons.

Two groups of neurons govern autism-like traits in model mice

Together, the neurons are part of the corticostriatal circuit, which has been implicated in autism.

By Peter Hess
15 April 2022 | 4 min read
Global map of 17,800 human proteins.

Proteome map identifies more than 90 percent of all human proteins

Researchers expand on the already enormous progress made on the Human Proteome Project

By Taylor White
9 December 2020 | 3 min read
DNA helix with mutation or deletion

Scores forecast effects of mutations in autism gene

A new analysis links individual mutations in a gene called PTEN to a person's odds of having autism, cancer or other conditions.

By Chloe Williams
8 July 2020 | 3 min read

Large mutations may explain diverse outcomes from autism gene

Deletions and duplications of long stretches of DNA may increase the likelihood of autism in people who have a mutation in a gene called PTEN.

By Laura Dattaro
24 February 2020 | 3 min read

Explore more from The Transmitter

10 standards for brain electrode-array recordings enhance reproducibility

Electrophysiology findings can vary widely from lab to lab, even among those using identical protocols. New guidelines set forth in a preprint should help.

By Elissa Welle
12 July 2024 | 5 min read
A hand holds a stack of speech bubbles.

Leveraging the power of community to strengthen clinical trials for rare genetic syndromes

Families can become not only participants but champions of these research efforts.

By Shafali Spurling Jeste
11 July 2024 | 7 min read

Accounting for a mosaic of sex differences: Q&A with Nicola Grissom

Breaking the binary view of sex traits can enable researchers to represent the broader complexity of behavior and cognition.

By Olivia Gieger
10 July 2024 | 7 min read