The HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) funding from the National Institutes of Health (NIH) supports USA organizations in rigorous basic and/or mechanistic pain research projects.
The purpose of this HEAL Initiative program is to: (1) support basic and mechanistic pain research from R15-eligible undergraduate-focused serving institutions, health professional schools, or graduate schools; (2) promote integrated, interdisciplinary research partnerships between Principal Investigators (PIs) from R15-eligible institutions and investigators from U.S. domestic institutions; and (3) enhance the pain research environment at the R15-eligible institution for health professional students, undergraduate and/or graduate students through active engagement in pain research.
Research Enhancement Awards (R15) support small-scale research projects at educational institutions in the USA that provide baccalaureate or advanced degrees for a significant number of the Nation’s research scientists but that have not been major recipients of NIH support.
Applicants may apply for up to 375,000 USD for up to 3 years.
Funding Opportunity Number: RFA-AT-25-003
Applications close on October 27, 2026.