The INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed) funding from the National Institutes of Health (NIH) INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) seeks to improve health and quality of life for individuals with Down syndrome.
This call aims to support new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE Project objectives:
- Component 1: Conduct targeted, high-risk, high-reward basic science studies on chromosome 21
- Component 2: Assemble a large study population of individuals with Down syndrome
- Component 3: Conduct clinical trials research inclusive of individuals with Down syndrome
Applications are open to researchers in the USA and worldwide. The grant provides up to 275,000 USD for 2 years.
Funding opportunity number: RFA-OD-27-003
The next application deadlines are:
- October 15, 2026
- June 15, 2027
- June 15, 2028