The future of fMRI

Recent articles

This series of essays explores new developments and challenges in human brain imaging.

Illustration of a brain with a window opening into it.

To understand the brain as a network organ, we must image cortical layers

Human neuroscience research has largely overlooked this spatial scale—which bridges cells and brain areas. But new advances in functional MRI technology are changing that.

By Laurentius Huber
2 June 2025 | 7 min listen
fMRI scans exiting a grain silo.

To make a meaningful contribution to neuroscience, fMRI must break out of its silo

We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.

By Avram Holmes
8 April 2025 | 8 min listen
Illustration of a toolbox with some tools replaced with lines of code.

New tools help make neuroimaging accessible to more researchers

A lack of programming experience can derail experimental aspirations. But custom software packages, web-based applications and video tutorials make functional MRI concepts easier to grasp.

By Andrew Jahn
5 March 2025 | 6 min listen
A hand holds multi-colored cubes.

Should we use the computational or the network approach to analyze functional brain-imaging data—why not both?

Emerging methods make it possible to combine the two tactics from opposite ends of the analytic spectrum, enabling scientists to have their cake and eat it too.

By Mac Shine
13 May 2024 | 7 min listen
Illustration of a hand reaching out to adjust a dial that sits in the middle of several images depicting brain activity and various behaviors.

To improve big data, we need small-scale human imaging studies

By insisting that every brain-behavior association study include hundreds or even thousands of participants, we risk stifling innovation. Smaller studies are essential to test new scanning paradigms.

By Emily S. Finn
15 April 2024 | 7 min read
An illustration of a mouse sitting in an armchair next to a framed picture of mouse brains

To make fMRI more clinically useful, we need to really get BOLD

A better understanding of the blood oxygen level dependent, or BOLD, signal requires more support for multimodal imaging studies.

By Evelyn Lake
22 January 2024 | 6 min read

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Explore more from The Transmitter

Whole-brain, bottom-up neuroscience: The time for it is now

Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.

By Edward Boyden, Konrad Körding
20 October 2025 | 9 min read
Collage of fruit fly and money.

Fly database secures funding for another year, but future remains in flux

The FlyBase team’s fundraising efforts have proven successful in the short term, but restoration of its federal grant remains uncertain.

By Calli McMurray
17 October 2025 | 3 min read
Nachum Ulanovsky sits against a black background with one bat in his hands and another with its wings spread above his head.

Diving in with Nachum Ulanovsky

With an eye toward realism, the neuroscientist, who has a new study about bats out today, creates microcosms of the natural world to understand animal behavior.

By Claudia López Lloreda
16 October 2025 | 14 min listen

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