Methods

Recent articles

Side view of a Tardigrade.

How tiny tardigrades could help tackle systems neuroscience questions

The eight-legged, millimeter-long animals reveal how small nervous systems produce complex behaviors and perceptual abilities, a preprint suggests.

By Dori Grijseels
11 March 2025 | 6 min read
A geometric figure looks out on an abstract horizon.

The limits of neuroscience

Truly understanding the brain requires a set of conditions we’re unlikely to meet: that knowledge about the brain is finite, and that we have both access to that knowledge and the means to understand it.

By Mark Humphries
10 March 2025 | 8 min read
Two scientists walk along interlocking rings.

Breaking the barrier between theorists and experimentalists

Many neuroscience students are steeped in an experiment-first style of thinking that leads to “random walk science.” Let’s not forget how theory can guide experiments toward deeper insights.

By Samuel Gershman
24 February 2025 | 6 min read
Abstract illustration of overlapping lines.

Claims of necessity and sufficiency are not well suited for the study of complex systems

The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?

By Grace Lindsay
7 February 2025 | 6 min read

Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down

5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.

By Shaena Montanari
4 February 2025 | 0 min watch
Different colored file folders.

Protocol-sharing site aims to ease administrative burden of animal research

The library of regulatory-compliant animal procedures offers experimental standards and specific language that researchers can borrow for their own legal paperwork.

By Calli McMurray
29 January 2025 | 4 min read
Violet-stained neurons in a serial transverse section from an embryonic spiny dogfish, a bottom-dwelling shark.

Digitization of ‘breathtaking’ neuroanatomy slide collection offers untapped research gold mine

Thousands of histological sections of vertebrate brains—including from spiny dogfish, turtles and more—are newly available online.

By Shaena Montanari
22 January 2025 | 3 min read

David Krakauer reflects on the foundations and future of complexity science

In his book “The Complex World,” Krakauer explores how complexity science developed, from its early roots to the four pillars that now define it—entropy, evolution, dynamics and computation.

By Paul Middlebrooks
14 January 2025 | 106 min listen
An illustration of a magnifying glass, checklists, and anonymous figures.

Spectrum 2024: Year in review

We round up our most notable autism stories of the past 12 months.

By Daisy Yuhas
23 December 2024 | 2 min read
Illustration of a shrew, sandpiper, locust, axolotl, monarch butterfly, African killifish, naked mole rat, octopus, bat and cichlid.

The non-model organism “renaissance” has arrived

Meet 10 neuroscientists bringing model diversity back with the funky animals they study.

Explore more from The Transmitter

Learning scientific rigor: Q&A with Konrad Kording and Hao Ye

The developers of a new open-access curriculum to teach rigor discuss confirmation bias and other common errors in scientific thinking, plus ways to avoid these missteps.

By Calli McMurray
19 March 2025 | 6 min read
Illustration of a woman sitting on a branch with a singing bird.

This paper changed my life: Stephanie Palmer on the ties between human speech and birdsong—and her ‘informal life coach’

A groundbreaking review by Allison Doupe, who was Palmer’s mentor, and Patricia Kuhl helped shape the field’s understanding of the neural and evolutionary dynamics of speech.

By Stephanie Palmer
18 March 2025 | 5 min read
Research image of mouse brains showing altered migration of upper-layer neurons.

Restoring excitation-inhibition balance in a mouse model of autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 17 March.

By Jill Adams
18 March 2025 | 2 min read